Publikace

2022

Gahura O., Chauhan P., Zíková A. (2022) Mechanisms and players of mitoribosomal biogenesis revealed in trypanosomatids. Trends in Parasitology, vol. 38(12), 1053-1067. https://doi.org/10.1016/j.pt.2022.08.010

Kotsyfakis S., Illiaki-Giannakoudaki E., Anagnostopoulos A., Papadokostaki E., Giannakoudakis K., Goumenakis M., Kotsyfakis M. (2022) The application of machine learning to imaging in hematological oncology: A scoping review. Front. Oncol. 12:1080988. doi: 10.3389/fonc.2022.1080988

Zhang P., Chen K., Svobodová M., Yang T., Lukeš J., Zhang J., Lun Z., Lai D. (2022) Does the fish-infecting Trypanosoma micropteri belong to Trypanosoma carassii? Folia Parasitologica 69. https://doi.org/10.14411/fp.2022.024

Štěpánek O., Čmoková A., Procházková E., Grobárová V., Černý J., Slapničková M., Zíková A., Kovařík M., Baszczyňski O. (2022) Piperazine-modified ketoconazole derivatives show increased activity against fungal and trypanosomatid pathogens. ChemMedChem, vol. 17(21). https://doi.org/10.1002/cmdc.202200385

Jirků M., Kašparová A., Lhotská Z., Oborník M., Brožová K., Petrželková K. J., Samaš P., Kadlecová O., Stensvold C. R., Jirků K. (2022) A cross-sectional study on the occurrence of the intestinal protist, Dientamoeba fragilis, in the gut-healthy volunteers and their animals. Int. J. Mol. Sci., 23, 15407. https://doi.org/10.3390/ijms232315407

Horáková E., Lecordier L., Cunha P. et al. (2022) Heme-deficient metabolism and impaired cellular differentiation as an evolutionary trade-off for human infectivity in Trypanosoma brucei gambiense. Nat Commun 13, 7075. https://doi.org/10.1038/s41467-022-34501-4

Gahura O., Mühleip A., Hierro-Yap C. et al. (2022) An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases. Nat Commun 13, 5989. https://doi.org/10.1038/s41467-022-33588-z

Benz C., Müller N., Kaltenbrunner S., Váchová H., Vancová M., Lukeš J., Varga V., Hashimi H. (2022) Kinetoplastid-specific X2-family kinesins interact with a kinesin-like pleckstrin homology domain protein that localizes to the trypanosomal microtubule quartet. Molecular Microbiology, vol. 118(3). https://doi.org/10.1111/mmi.14958

Singh V., Hada R. S., Jain R., Vashistha M., Kumari G., Singh S., Sharma N., Bansal M., Poonam, Zoltner M., Caffrey C. R., Rathi B., Singh S. (2022) Designing and development of phthalimides as potent anti-tubulin hybrid molecules against malaria. European Journal of Medicinal Chemistry, vol. 239. https://doi.org/10.1016/j.ejmech.2022.114534

Lemke C., Jílková A., Ferber D., Braune A, On A., Johe P., Zíková A., et al. (2022) Two tags in one probe: Combining fluorescence- and biotin-based detection of the trypanosomal cysteine protease rhodesain. Chemistry – a European Journal. https://doi.org/10.1002/chem.202201636

Vaňková K., Doleželová E., Tloušťová E., Hocková D., Zíková A., Janeba Z. (2022) Synthesis and anti-trypanosomal evaluation of novel N-branched acyclic nucleoside phosphonates bearing 7-aryl-7-deazapurine nucleobase. European Journal of Medicinal Chemistry, vol. 239 https://doi.org/10.1016/j.ejmech.2022.114559

Pilátová J., Pánek T., Oborník M. et al. (2022) Revisiting biocrystallization: purine crystalline inclusions are widespread in eukaryotes. ISME J, 16, 2290-2294. https://doi.org/10.1038/s41396-022-01264-1

Medina J. M., Abbas M. N., Bensaoud C., Hackenberg M., Kotsyfakis M. (2022) Bioinformatic analysis of Ixodes ricinus long non-coding RNAs predicts their binding ability of host miRNAs. Int. J. Mol. Sci., 23, 9761. https://doi.org/10.3390/ijms23179761

Stanicka A., Cichy A., Bulantová J., Labecka A. M., Cmiel A. M., Templin J., Horák P., Zbikowska E. (2022) Thinking “outside the box”: The effect of nontarget snails in the aquatic community on mollusc-borne diseases. Science of The Total Environment, vol. 845. https://doi.org/10.1016/j.scitotenv.2022.157264

Trentelman J. J. A., de Vogel F. A., Colstrup E., Šíma R., Coumou J., Koetsveld J., Klouwens M. J., Nayak A., Ersoz J., Barriales D., Tomás-Cortázar J., Narasimhan S., Hajdušek O., Anguita J., Hovius J. W. (2022) Identification of novel conserved Ixodes vaccine candidates; a promising role for non-secreted salivary gland proteins. Vaccine, vol. 40(52), 7593-7603. https://doi.org/10.1016/j.vaccine.2022.10.032

Lukeš J., Kachale A., Votýpka J., Butenko A., Field M. C. (2022) African trypanosome strategies for conquering new hosts and territories: the end of monophyly? Trends in parasitology, vol. 38(9), 724-736. https://doi.org/10.1016/j.pt.2022.05.011

Magri A., Bianchi C., Chmelová Ľ, Caffara M., Galuppi R., Fioravanti M., Yurchenko V., Kostygov A. Y. (2022) Roe deer (Capreolus capreolus) are a novel potential reservoir for human visceral leishmaniasis in the Emilia-Romagna region of northeastern Italy. International Journal for parasitology, vol 52(12), 745-750. https://doi.org/10.1016/j.ijpara.2022.09.002

Procházková M., Füzik T., Grybchuk D., Yurchenko V., Plevka P. (2022) Virion structure of Leishmania RNA virus 1. Virology, vol. 577, 149-154 https://doi.org/10.1016/j.virol.2022.09.014

Barcyté D., Zátopková M., Němcová Y., Richtář M., Yurchenko T., Jaške K., Fawley K. P., Škaloud P., Ševčíková T., Fawley M. W., Eliáš M. (2022) Redefining Chlorobotryaceae as one of the principal and most diverse lineages of eustigmatophyte algae. Molecular phylogenetics and Evolution, vol. 177. https://doi.org/10.1016/j.ympev.2022.107607

Belinky F., Byková A., Yurchenko V., Rogozin I. B. (2022). No evidence for widespread positive selection on double substitutions within codons in primates and yeasts. Front. Genet. 13:991249 doi: 10.3389/fgene.2022.991249

Saura A., Zakharova A., Klocek D., Gerasimov E. S., Butenko A., Macedo D. H., Serviené E. et al. (2022) Elimination of LRVs elicits different responses in Leishmania spp. mSphere, vol. 7(4). https://doi.org/10.1128/msphere.00335-22

Zoltner M., Field M. C. (2022) Microbe profile: Euglena gracilis: photogenic, flexible and hardy. Microbiology, vol. 168(9). https://doi.org/10.1099/mic.0.001241

Vojtechova I., Machacek T., Kristofikova Z., Stuchlik A., Petrasek T. (2022) Infectious origin of Alzheimer’s disease: Amyloid beta as a component of brain antimicrobial immunity. PLoS Pathog 18(11): e1010929. https://doi.org/10.1371/journal.ppat.1010929

Kazamia E., Mach J., McQuaid J. B., Gao X., Coale T. H., Malych R., Camadro J. M., Lesuisse E., Allen A. E., Bowler C., Šuťák R. (2022) In vivo localization of iron starvation induced proteins under variable iron supplementation regimes in Phaeodactylum tricornutum. Plant Direct, vol. 6(12), https://doi.org/10.1002/pld3.472

Zítek J., Füssy Z., Treitli S. C., Peña-Diaz P., Vaitová Z., Zavadska D., Harant K., Hampl V. (2022) Reduced mitochondria provide an essential function for the cytosolic methionine cycle. Current biology, vol. 32(23), 5057-5068.e5 https://doi.org/10.1016/j.cub.2022.10.028

Votýpka J., Stříbrná E., Modrý D., Bryja J., Bryjová A., Lukeš J. (2022) Unexpectedly high diversity of trypanosomes in small sub-Saharan mammals. International Journal for parasitology, vol 52(10), 647-658. https://doi.org/10.1016/j.ijpara.2022.06.002

Pondeville E., Failloux A. B., Simard F., Volf P., Crisanti A., Haghighat-Khah R. E., Busquets N., Abad F. X., Wilson A. J., Bellini R., Arnaud S. M., Kohl A., Veronesi E. (2022) Infravec2 guidelines for the design and operation of containment level 2 and 3 insectaries in Europe. Pathogens and Global Health DOI: 10.1080/20477724.2022.2108639

Messahel N. E., Benallal K. E., Halada P., Lafri I., Manseur H., Hakem A., Houali K., Harrat Z., Volf P., Dvořák V. (2022) Identification of blood source preferences and Leishmania infection in sand flies (Diptera: Psychodidae) in north-eastern Algeria. Veterinary parasitology, vol. 31, e100729 https://doi.org/10.1016/j.vprsr.2022.100729

Zakharova A., Albanaz A. T. S., Opperdoes F. R., Škodová-Sveráková I., Zagirova D., Saura A., et al. (2022) Leishmania guyanensis M4147 as a new LRV1-bearing model parasite: Phosphatidate phosphatase 2-like protein controls cell cycle progression and intracellular lipid content. PLoS Negl Trop Dis 16(6): e0010510. https://doi.org/10.1371/journal.pntd.0010510

Pacáková L, Harant K., Volf P., Leštinová T. (2022) Three types of Leishmania mexicana amastigotes: Proteome comparison by quantitative proteomic analysis. Front. Cell. Infect. Microbiol. 12:1022448 doi: 10.3389/fcimb.2022.1022448

Tachezy J., Makki A., Hrdý I. (2022) The hydrogenosome of Trichomonas vaginalis. The Journal of eukaryotic microbiology, vol. 69(6). https://doi.org/10.1111/jeu.12922

Rada P., Hrdý I., Zdrha A., Narayanasamy R. K., Smutná T., Horáčková J., Harant K., Beneš V., Ong S. C., Tsai C. Y., Luo H. W., Chiu C. H., Tang P., Tachezy J. (2022) Double-stranded RNA viruses are released from Trichomonas vaginalis inside small extracellular vesicles and modulate the exosomal cargo. Front. Microbiol. 13:893692. doi: 10.3389/fmicb.2022.893692

Záhonová K., Treitli S. C., Le T. et al. (2022) Anaerobic derivates of mitochondria and peroxisomes in the free-living amoeba Pelomyxa schiedti revealed by single-cell genomics. BMC Biol 20, 56. https://doi.org/10.1186/s12915-022-01247-w

Smutná T., Dohnálková A., Šuťák R., Narayanasamy R. K., Tachezy J., Hrdý I. (2022) A cytosolic ferredoxin-independent hydrogenase possibly mediates hydrogen uptake in Trichomonas vaginalis. Current biology, vol. 32(1), 124-135 https://doi.org/10.1016/j.cub.2021.10.050

Zimmann N., Rada P., Žárský V., Smutná T., Záhonová K., Dacks J., Harant K., Hrdý I., Tachezy J. (2022) Proteomic analysis of Trichomonas vaginalis phagolysosome, lysosomal targeting, and unconventional secretion of cysteine peptidases. Molecullar and cellular proteomics, vol 21(1): e100174 https://doi.org/10.1016/j.mcpro.2021.100174

George E. E., Tashyreva D., Kwong W. K., Okamoto N., Horák A., Husník F., Lukeš J., Keeling P. J. (2022). Gene transfer agents in bacterial endosymbionts of microbial eukaryotes. Genome biology and Evolution, vol. 14(7). https://doi.org/10.1093/gbe/evac099

Tashyreva D., Simpson A. G. B., Prokopchuk G., Škodová-Sveráková I., Butenko A., Hammond M., George E. E., Flegontova O., Záhonová K., Faktorová D., Yabuki A., Horák A., Keeling P. J., Lukeš J. (2022) Diplonemids – A review on "new" flagellates on the oceanic block. Protist, vol 173(2), 125868. https://doi.org/10.1016/j.protis.2022.125868

Klejch T., Keough D. T., King G., Doleželová E., Česnek M., Buděšínský M., Zíková A., Janeba Z., Guddat L. W., Hocková D. (2022) Stereo-defined acyclic nucleoside phosphonates are selective and potent inhibitors of parasite 6-oxopurine phosphoribosyltransferases. J. Med. Chem. 65, 5, 4030–4057 https://doi.org/10.1021/acs.jmedchem.1c01881

Hammond M., Dorrell R. G., Speijer D., Lukeš J. (2022) Eukaryotic cellular intricacies shape mitochondrial proteomic complexity. BioEssays, vol 44(5) https://doi.org/10.1002/bies.202100258

Prokopchuk G., Korytář T., Juricová V. et al. (2022) Trophic flexibility of marine diplonemids - switching from osmotrophy to bacterivory. ISME J 16, 1409–1419. https://doi.org/10.1038/s41396-022-01192-0

Kuppannan A., Jiang Y. Y., Maier W., Liu C., Lang C. F., Cheng C. Y., et al. (2022) A novel membrane complex is required for docking and regulated exocytosis of lysosome-related organelles in Tetrahymena thermophila. PLoS Genet 18(5): e1010194. https://doi.org/10.1371/journal.pgen.1010194

Zíková A. (2022) Mitochondrial adaptations throughout the Trypanosoma brucei life cycle. The Journal of eukaryotic microbiology. https://doi.org/10.1111/jeu.12911

Hegedüsová E., Maršalová V., Kulkarni S., Paris Z. (2022) Trafficking and/or division: Distinct roles of nucleoporins based on their location within the nuclear pore complex. RNA Biology, 19:1, 650 661, doi: 10.1080/15476286.2022.2067711

Sharaf A., Vijayanathan M., Oborník M., Mozgová I. (2022) Phylogenetic profiling resolves early emergence of PRC2 and illuminates its functional core. Life Science Alliance. DOI: 10.26508/lsa.202101271

Medina J. M., Jmel M. A., Cuveele B., Gómez-Martín C., Aparicio-Puerta E., Mekki I., Kotál J., Martins L. A., Hackenberg M., Bensaoud C., Kotsyfakis M. (2022) Transcriptomic analysis of the tick midgut and salivary gland responses upon repeated blood-feeding on a vertebrate host. Front. Cell. Infect. Microbiol. 12:919786. doi: 10.3389/fcimb.2022.919786

Urbanová V., Kalinová E., Kopáček P., Šíma R. (2022) Experimental infection of mice and ticks with the human isolate of Anaplasma phagocytophilum NY-18. Pathogens, 820. https://doi.org/10.3390/pathogens11070820

Guizzo M. G., Dolezelikova K., Neupane S. et al. (2022) Characterization and manipulation of the bacterial community in the midgut of Ixodes ricinus. Parasites Vectors 15, 248. https://doi.org/10.1186/s13071-022-05362-z

Abbas M. N., Chlastáková A., Jmel M. A., Iliaki-Giannakoudaki E., Chmelař J., Kotsyfakis M. (2022) Serpins in tick physiology and tick-host interaction. Front. Cell. Infect. Microbiol. 12:892770. doi: 10.3389/fcimb.2022.892770

Perner J., Hajdušek O., Kopáček P. (2022) Independent somatic distribution of heme and iron in ticks. Current opinion in insect science, vol 51, 100916 https://doi.org/10.1016/j.cois.2022.100916

Winkelmann F., Gesell Salazar M., Hentschker C. et al. (2022) Comparative proteome analysis of the tegument of male and female adult Schistosoma mansoni. Sci Rep 12, 7569. https://doi.org/10.1038/s41598-022-11645-3

Vondráček O., Mikeš L., Talacko P., Leontovyč R., Bulantová J., Horák P. (2022) Differential proteomic analysis of laser-microdissected penetration glands of avian schistosome cercariae with a focus on proteins involved in host invasion. International Journal for parasitology, vol. 52(6), 343-358. https://doi.org/10.1016/j.ijpara.2021.12.003

Grechnikova M., Arbon D., Ženíšková K., Malych R., Mach J., Krejbichová L., Šimáčková A., Šuťák R. (2022) Elucidation of iron homeostasis in Acanthamoeba castellanii. International Journal for parasitology, vol. 52(8), 497-508. https://doi.org/10.1016/j.ijpara.2022.03.007

Ženíšková K., Grechnikova M., Šuťák R. (2022) Copper metabolism in Naegleria gruberi and its deadly relative Naegleria fowleri. Front. Cell. Dev. Biol. 10:853463. doi: 10.3389/fcell.2022.853463

Arbon D., Ženíšková K., Šubrtová K., Mach J., Štursa J., Machado M., Zahedifard F. et al. (2022). Repurposing of Mitotam: Novel anti-cancer drug candidate exhibits potent activity against major protozoan and fungal pathogens. ASM Journals – Antimicrobial agents and chemotherapy, vol. 66(8). https://doi.org/10.1128/aac.00727-22

Horáčková V., Voleman L, Hagen K. D., Petrů M., Vinopalová M., Weisz F., Janowicz N., Marková L., Motyčková A., Najdrová V., Tůmová P., Dawson S. C., Doležal P. (2022). Efficient CRISPR/Cas9-mediated gene disruption in the tetraploid protist Giardia intestinalis. Open Biol.12210361210361 http://doi.org/10.1098/rsob.210361

Fry M. Y., Najdrová V., Maggiolo A. O. et al. (2022) Structurally derived universal mechanism for the catalytic cycle of the tail-anchored targeting factor Get3. Nat Struct Mol Biol 29, 820–830. https://doi.org/10.1038/s41594-022-00798-4

Kornalíková M., Hampl V., Treitli S. C. (2022) Investigation of the genome sizes and ploidy within the genus Monocercomonoides. The Journal of eukaryotic mikrobiology, vol. 69, 4. https://doi.org/10.1111/jeu.12925

Willen L., Milton P., Hamley J. I. D., Walker M., Osei-Atweneboana M. Y., Volf P., et al. (2022) Demographic patterns of human antibody levels to Simulium damnosum s.l. saliva in onchocerciasis-endemic areas: An indicator of exposure to vector bites. PLoS Negl Trop Dis 16(1): e0010108. https://doi.org/10.1371/journal.pntd.0010108

Ticha L., Sadlova J., Bates P. et al. (2022) Experimental infections of sand flies and geckos with Leishmania (Sauroleishmania) adleri and Leishmania (S.) hoogstraali. Parasites Vectors 15, 289. https://doi.org/10.1186/s13071-022-05417-1

Sádlová J., Bacíková D., Bečvář T., Vojtková B., England M., Shaw J., Volf P. (2022) Porcisia transmission by prediuresis of sand flies. Front. Cell. Infect. Microbiol. 12:981071. https://doi.org/10.3389/fcimb.2022.981071

Piel L., Rajan K. S., Bussotti G., Varet H., Legendre R., Proux C., et al. (2022) Experimental evolution links post-transcriptional regulation to Leishmania fitness gain. PLoS Pathog 18(3): e1010375. https://doi.org/10.1371/journal.ppat.1010375

de Oliveira Miranda D. E., da Silva Sales K. G., Aguiar Figueredo L., Andrade de Oliveira S., Vasconcelos do Nascimento A., Lira Torres D. J., Sůmová P., Volf P., Brandão-Filho S. P., da Cunha Gonçalves de Albuquerque S., Barros de Lorena V. M., Dantas-Torres F. (2022) Effects of Migonemyia migonei salivary gland homogenates on Leishmania (Viannia) braziliensis infection in BALB/c mice. Acta Tropica, vol 227, 106271. https://doi.org/10.1016/j.actatropica.2021.106271

Linhart P., Bandouchova H., Zukal J., Votýpka J., Baláž V., Heger T., Kalocsanyiova V., Kubickova A., Nemcova M., Sedlackova J., Seidlova V., Veitova L., Vlaschenko A., Divinova  R., Pikula J. (2022) Blood parasites and health status of hibernating and non-hibernating Noctule bats (Nyctalus noctula). Microorganisms. 10, 1028 https://doi.org/10.3390/microorganisms10051028

Mendoza-Roldan J. A., Votýpka J., Bandi C., Epis S., Modrý D., Tichá L., Volf P., Otranto D. (2022) Leishmania tarentolae: A new frontier in the epidemiology and control of the leishmaniases. Transboundary and emerging diseases. https://doi.org/10.1111/tbed.14660

Gerasimov E. S., Ramirez-Barrios R., Yurchenko V., Zimmer S. L. (2022) Trypanosoma cruzi strain and starvation-driven mitochondrial RNA editing and transcriptome variability. RNA, 993-1012. doi: 10.1261/rna.079088.121.

Kostygov A. Y., Frolov A. O., Malysheva M. N. et al. (2022) Development of two species of the Trypanosoma theileri complex in tabanids. Parasites Vectors 15, 95. https://doi.org/10.1186/s13071-022-05212-y

Chmelová Ľ., Bianchi C., Albanaz A. T. S., Režnarová J., Wheeler R., Kostygov A. Y., Kraeva N., Yurchenko V. (2022) Comparative analysis of three trypanosomatid catalases of different origin. Antioxidants. 11, 46. https://doi.org/10.3390/antiox11010046

Vargová R., Hanousková P., Salamonová J., Žihala D., Silberman J. D., Eliáš M., Čepička I. (2022) Evidence for an independent hydrogenosome-to-mitosome transition in the CL3 lineage of fornicates. Front. Microbiol. 13:866459. doi: 10.3389/fmicb.2022.866459

Dewees S. I., Vargová R., Hardin K. R., Turn R. E., Devi S., Linnert J., Wolfrum U., Caspary T., Eliáš M., Kahn R. A. (2022) Phylogenetic profiling and cellular analyses of ARL16 reveal roles in traffic of IFT140 and INPP5E. Molecular Biology of the Cell. 33, 4. https://doi.org/10.1091/mbc.E21-10-0509-T

Pánek T., Barcyté D., Treitli S. C. et al. (2022) A new lineage of non-photosynthetic green algae with extreme organellar genomes. BMC Biol 20, 66. https://doi.org/10.1186/s12915-022-01263-w

Oborník M. (2022) Organellar evolution: A path from benefit to dependence. Microorganisms 10, 122. https://doi.org/10.3390/microorganisms10010122 

Perner J., Kucera M., Frantova H., Urbanova V., Kopacek P., Sima R. (2022) Lyme disease transmission by severely impaired ticks. Open Biol. (2):210244. https://royalsocietypublishing.org/doi/10.1098/rsob.210244

Kořený L., Oborník M., Horáková E., Waller R. F., Lukeš J. The convoluted history of haem biosynthesis. Biol Rev Camb Philos Soc. 2022;97(1):141-162. doi:10.1111/brv.12794

Macháček T., Leontovyč R., Šmídová B., Majer M., Vondráček O., Vojtěchová I., Petrásek T., Horák P. (2022): Mechanisms of the host immune response and helminth-induced pathology during Trichobilharzia regenti (Schistosomatidae) neuroinvasion in mice. PLoS Pathogens 18: e1010302. DOI: 10.1371/journal.ppat.1010302 [IF2020=6.823]

Malych R., Stopka P., Mach J., Kotabová E., Prášil O., Sutak R. (2022) Flow cytometry-based study of model marine microalgal consortia revealed an ecological advantage of siderophore utilization by the dinoflagellate Amphidinium carterae. Comput Struct Biotechnol J. DOI: 10.1016/j.csbj.2021.12.023

Narayanasamy R. K., Rada P., Zdrha A., Ranst M., Neyts J. & Tachezy J. (2022). Cytidine nucleoside analog is an effective antiviral drug against Trichomonasvirus. Journal of Microbiology, Immunology and infection: Volume 55, Issue 2, pages 191-198. https://doi.org/10.1016/j.jmii.2021.08.008

2021

Verner Z., Žárský V., Le T., Narayanasamy R. K., Rada P., Rozbeský D., et al. (2021) Anaerobic peroxisomes in Entamoeba histolytica metabolize myo-inositol. PLoS Pathog 17(11): e1010041. https://doi.org/10.1371/journal.ppat.1010041

Tortorelli G., Pettollino F., Lai De-Hua, Tomčala A., Bacic A., Oborník M., Lukeš J., McFadden G. I. (2021). The cell wall polysaccharides of a photosynthetic relative of apicomplexans, Chromera velia. Journal of Phycology. https://doi.org/10.1111/jpy.13211

Petrů M., Dohnálek V., Füssy Z., Doležal P. (2021) Fates of sec, tat, and YidC translocases in mitochondria and other eukaryotic compartments. Molecular Biology and Evolution, Volume 38, Issue 12. Pages 5241–5254. https://doi.org/10.1093/molbev/msab253

Blanvillain C., Saavedra S., Withers T., Votýpka J., Laroucau K., Lowenski S., Modrý D. (2021) Screening of diseases in wild exotic birds on Tahiti Island – implications for French Polynesian conservation. Pacific Conservation Biology 27, 284-295. https://doi.org/10.1071/PC20049

Tůmová P., Voleman L., Klingl A. et al. Inheritance of the reduced mitochondria of Giardia intestinalis is coupled to the flagellar maturation cycle. BMC Biol 19, 193 (2021). https://doi.org/10.1186/s12915-021-01129-7

Poláková E., Záhonová K., Albanaz A., Butenko A., Lukeš J., & Yurchenko V. (2021). Diverse telomeres in trypanosomatids. Parasitology, 148(10), 1254-1270. doi:10.1017/S0031182021000378

Kalčic F., Frydrych J., Doleželová E., Slapničková M., Pachl P., Poštová-Slavětínská L., Dračínský M., Hocková D., Zíková A., Janeba Z. (2021). C1´-Branched acyclic nucleoside phosphonates mimicking adenosine monophosphate: Potent inhibitors of Trypanosoma brucei adenine phosphoribosyltransferase. European Journal of Medicinal Chemistry: Volume 225, 113798 https://doi.org/10.1016/j.ejmech.2021.113798

Perner J., Hatalova T., Cabello-Donayre M., Urbanova V., Sojka D., Frantova H., Hartmann D., Jirsova D., Pérez-Victoria J. M. & Kopacek P. (2021). Haem-responsive gene transporter enables mobilization of host haem in ticks. Open Biology: Volume 11, Issue 9. https://doi.org/10.1098/rsob.210048

Kotál J., Polderdijk S. G. I., Langhansová H., Ederová M., Martins L. A., Beránková Z., Chlastáková A., Hajdušek O., Kotsyfakis M., Huntington J. A., Chmelař J. Ixodes ricinus salivary serpin Iripin-8 inhibits the intrinsic pathway of coagulation and complement. International Journal of Molecular Sciences. 2021; 22(17):9480. https://doi.org/10.3390/ijms22179480

Paris Z. (2021). Nuclear tRNA export in trypanosomes: A journey full of twists and turns guided by tRNA modifications. Parasitology, 148(10), 1219-1222. doi:10.1017/S0031182021000482

Kostygov A. Y., Grybchuk D., Kleschenko Y., Chistyakov D. S., Lukashev A. N., Gerasimov E. S., Yurchenko V. Analyses of Leishmania-LRV co-phylogenetic patterns and evolutionary variability of viral proteins. Viruses. 2021; 13(11):2305. https://doi.org/10.3390/v13112305

Poláková E., Albanaz A. T. S., Zakharova A., Novozhilova T. S., Gerasimov E. S., Yurchenko V. (2021) Ku80 is involved in telomere maintenance but dispensable for genomic stability in Leishmania mexicana. PLoS Negl Trop Dis 15(12): e0010041. https://doi.org/10.1371/journal.pntd.0010041

Zakharova A., Saura A., Butenko A., Podešvová L., Warmusová S., Kostygov A. Y., Nenarokova A., Lukeš J., Opperdoes F. R., Yurchenko V. (2021). A new model trypanosomatid, Novymonas esmeraldas: Genomic perception of its “Candidatus Pandoraea novymonadis“ endosymbiont. Eukaryotic Cells, https://doi.org/10.1128/mBio.01606-21

Vargová R., Wideman J. G., Derelle R., Klimeš V., Kahn R. A., Dacks J. B., Eliáš M. A eukaryote-wide perspective on the diversity and evolution of the ARF GTPase protein family. Genome Biology and Evolution, Volume 13, Issue 8, August 2021, evab157. https://doi.org/10.1093/gbe/evab157

Dixit S., Kessler A. C., Henderson J., Pan X., Zhao R., D'Almeida G. S., Kulkarni S., Rubio M. A. T., Hegedűsová E., Ross R. L., Limbach P. A., Green B. D., Paris Z., Alfonzo J.D.  Dynamic queuosine changes in tRNA couple nutrient levels to codon choice in Trypanosoma brucei. Nucleic Acids Res. 2021 Dec 16;49(22):12986-12999. doi: 10.1093/nar/gkab1204. (IF=16.97)

Kopáček P., Šíma R., Perner J. (2021) An mRNA-based anti-tick vaccine catches ticks red-handed.  Sci Transl Med. 2021 Nov 17;13(620):eabm2504. https://www.science.org/doi/10.1126/scitranslmed.abm2504

Šnebergerová P., Bartošová-Sojková P., Jalovecká M., Sojka D. (2021) Plasmepsin-like aspartyl proteases in Babesia. Pathogens Sep 26;10(10):1241.  https://www.mdpi.com/2076-0817/10/10/1241

Stairs C. W., Táborský P., Salomaki E. D., Kolisko M., Pánek T., Eme L., Hradilová M., Vlček Č., Jerlström-Hultqvist J., Roger A. J., Čepička I. (2021) Anaeramoebae are a divergent lineage of eukaryotes that shed light on the transition from anaerobic mitochondria to hydrogenosomes. Curr Biol. 31:5605-5612.e5

Treitli S. C., Peña-Diaz P., Hałakuc P., Karnkowska A., Hampl V. High quality genome assembly of the amitochondriate eukaryote Monocercomonoides exilis. Microb Genom. 2021 Dec;7(12). doi: 10.1099/mgen.0.000745. PMID: 34951395.

Tonelli G. B., Andrade J. D., Campos A. M., Margonari C., Amaral A. R., Volf P., Shaw E. J., Hamilton J. G. C. (2021) Examination of the interior of sand fly (Diptera: Psychodidae) abdomen reveals novel cuticular structures involved in pheromone release: Discovering the manifold. PLOS NEGLECTED TROPICAL DISEASES 15, Article Number e0009733.

Bahia A. C., Barletta A. B. F., Pinto L. C., Orfanó A. S., Nacif-Pimenta R., Volfova V., Volf P., Secundino N. F. C., Fernandes F. F., Pimenta P. F. P. (2021) Morphological characterization of the antennal sensilla of the afrotropical sand fly, Phlebotomus duboscqi (Diptera: Psychodidae).  Journal of Medical Entomology 58, 634–645.

Kykalova B., Ticha L., Volf P., Loza Telleria E. (2021) Phlebotomus papatasi antimicrobial peptides in larvae and females and a gut-specific defensin upregulated by Leishmania major infection. Microorganisms 9, 2307.

Sumova P., Sanjoba C., Willen L., Polanska N., Matsumoto Y., Noiri E., Paul S. K., Ozbel Y., Volf P. (2021) PpSP32-like protein as a marker of human exposure to Phlebotomus argentipes in Leishmania donovani foci in Bangladesh. International Journal for Parasitology 51: 1059-

Ticha L., Kykalova B., Sadlova J., Gramiccia M., Gradoni L., Volf P. (2021) Development of various Leishmania (Sauroleishmania) tarentolae strains in three Phlebotomus species. Microorganisms 9: 2256.

Husnik F., Tashyreva D., Boscaro V., Geoge E. E., Lukeš J., Keeling P. J. (2021). Bacterial and archaeal symbioses with protists. Current Biology: Volume 31, Issue 13, Pages R862-R877. https://doi.org/10.1016/j.cub.2021.05.049

Kulkarni S., Rubio M. A. T., Hegedüsová E., Ross R. L., Limbach P. A., Alfonzo J. D., Paris Z. Preferential import of queuosine-modified tRNAs into Trypanosoma brucei mitochondrion is critical for organellar protein synthesis. Nucleic Acids Research, Volume 49, Issue 14, 20 August 2021. Pages 8247–8260, https://doi.org/10.1093/nar/gkab567

Paris Z., Svobodová M., Kachale A., Horáková E., Nenarokova A. & Lukeš J. (2021). A mitochondrial cytidine deaminase is responsible for C to U editing of tRNATrp to decode the UGA codon in Trypanosoma brucei. RNA Biology, 18:sup1, 278-286. DOI: 10.1080/15476286.2021.1940445

Doleželová E., Klejch T., Špaček P. et al. Acyclic nucleoside phosphonates with adenine nucleobase inhibit Trypanosoma brucei adenine phosphoribosyltransferase in vitro. Sci Rep 11, 13317 (2021). https://doi.org/10.1038/s41598-021-91747-6

Smilansky V., Jirků M., Milner D. S., Ibáñez R., Gratwicke B., Nicholls A., Lukeš J., Chambouvet A. & Richards T. A. (2021). Expanded host and geographic range of tadpole associations with the Severe Perkinsea infection group. Volume 17, Issue 6. https://doi.org/10.1098/rsbl.2021.0166

Mishra A., Naseer Kaur J., McSkimming D. I., Hegedüsová E., Dubey A. P., Ciganda M., Paris Z., Read L. K. (2021). Selective nuclear export of mRNAs is promoted by DRBD18 in Trypanosoma brucei. https://doi.org/10.1111/mmi.14773

Richtová J., Sheiner L., Gruber A., Yang S. M., Kořený L., Striepen B., Oborník M. Using diatom and apicomplexan models to study the heme pathway of Chromera velia. International Journal of Molecular Sciences. 2021; 22(12):6495. https://doi.org/10.3390/ijms22126495

Cadena L. R., Gahura O., Panicucci B., Zíková A., Hashimi H. (2021). Mitochondrial contact site and cristae organization system and F1FO-ATP synthase crosstalk is a fundamental property of mitochondrial cristae. mSphere, e00327-21, Volume 6, Issue 3. https://journals.asm.org/doi/abs/10.1128/mSphere.00327-21

Sojka D., Šnebergerová P., Robbertse L. Protease inhibition—An established strategy to combat infectious diseases. International Journal of Molecular Sciences. 2021; 22(11):5762. https://doi.org/10.3390/ijms22115762

Záhonová K., Lax G., Sinha S. D. et al. Single-cell genomics unveils a canonical origin of the diverse mitochondrial genomes of euglenozoans. BMC Biol 19, 103 (2021). https://doi.org/10.1186/s12915-021-01035-y

Lopes A. L. K., Kriegová E., Lukeš J., Krieger M. A., Ludwig A. (2021) Distribution of Merlin in eukaryotes and first report of DNA transposons in kinetoplastid protists. PLoS ONE 16(5): e0251133. https://doi.org/10.1371/journal.pone.0251133

Oborník M. (2021) Enigmatic evolutionary history of porphobilinogen deaminase in eukaryotic phototrophs. Biology 10, no. 5: 386. https://doi.org/10.3390/biology10050386

Salomaki E. D., Terpis K. X., Rueckert S. et al. Gregarine single-cell transcriptomics reveals differential mitochondrial remodeling and adaptation in apicomplexans. BMC Biol 19, 77 (2021). https://doi.org/10.1186/s12915-021-01007-2

Pyrih J., Pánek T., Durante I. M., Rašková V., Cimrhanzlová K., Kriegová E., Tsaousis A. D., Eliáš M., Lukeš J. Vestiges of the bacterial signal recognition particle-based protein targeting in mitochondria. Molecular Biology and Evolution, Volume 38, Issue 8, August 2021, Pages 3170–3187. https://doi.org/10.1093/molbev/msab090

Bílý T., Sheikh S., Mallet A., Bastin P., Pérez-Morga D., Lukeš J., Hashimi H. (2021) Ultrastructural changes of the mitochondrion during the life cycle of Trypanosoma brucei. https://doi.org/10.1111/jeu.12846

Turnšek J., Brunson J. K., del Pilar Martinez Viedma M., Deerinck T. J., Horák A., Oborník M., Bielinski V. A., Allen A. E. (2021) Proximity proteomics in a marine diatom reveals a putative cell surface-to-chloroplast iron trafficking pathway. eLife 10:e52770. https://doi.org/10.7554/eLife.52770

Padilla-Mejia N. E., Koreny L., Holden J., Vancová M., Lukeš J., Zoltner M., Field M. C. A hub-and-spoke nuclear lamina architecture in trypanosomes. J Cell Sci. 2021 Jun 15;134(12):jcs251264. 

Sharma P. P., Kumar S., Srivastava S., Srivastava M., Jee B., Gorobets N. Y., Kumar D., Kumar M., Asthana S., Zhang P., Poonam, Zoltner M., Rathi B. Computational study of novel inhibitory molecule, 1-(4-((2S,3S)-3-amino-2-hydroxy-4-phenylbutyl)piperazin-1-yl)-3-phenylurea, with high potential to competitively block ATP binding to the RNA dependent RNA polymerase of SARS-CoV-2 virus. J Biomol Struct Dyn. 2021 Jun 21:1-19. 

Hammond M., Zoltner M., Garrigan J., Butterfield E., Varga V., Lukeš J., Field M. C. The distinctive flagellar proteome of Euglena gracilis illuminates the complexities of protistan flagella adaptation. New Phytol. 2021 Jul 22.

Vorel J., Cwiklinski K., Roudnický P., Ilgová J., Jedličková L., Dalton J. P., Mikeš L., Gelnar M., Kašný M. (2021): Eudiplozoon nipponicum (Monogenea, Diplozoidae) and its adaptation to haematophagy as revealed by transcriptome and secretome profiling. BMC Genomics 22: 274. DOI: 10.1186/s12864-021-07589-z [IF2020=3.969]

Soukal P., Hrdá Š., Karnkowska A., Milanowski R., Szabová J., Hradilová M., Strnad H., Vlček Č., Čepička I., Hampl V. Heterotrophic euglenid Rhabdomonas costata resembles its phototrophic relatives in many aspects of molecular and cell biology. Sci Rep. 2021 Jun 22;11(1):13070. doi: 10.1038/s41598-021-92174-3. PMID: 34158556; PMCID: PMC8219788.

Sulesco T., Kasap O. E., Halada P., Oguz G., Rusnac D., Gresova M., Alten B., Volf P., Dvorak V. (2021) Phlebotomine sand fly survey in the Republic of Moldova: species composition, distribution and host preferences. PARASITES & VECTORS 14: Article Number 371.

Corrales R. M., Vaselek S., Neish R., Berry L., Brunet C. D., Crobu L., Kuk N., Mateos-Langerak J., Robinson D. R., Volf P., Mottram J. C., Sterkers Y., Bastien P. (2021) The kinesin of the flagellum attachment zone in Leishmania is required for cell morphogenesis, cell division and virulence in the mammalian host. PLoS Pathogens 17: e1009666.

Telleria E. L., Tinoco-Nunes B., Lestinova T., De Avellar L. M., Tempone A. J., Pitaluga A. N., Volf P., Traub-Cseko Y. M.  (2021) Lutzomyia longipalpis antimicrobial peptides: Differential expression during development and potential involvement in vector interaction with microbiota and Leishmania. MICROORGANISMS 9: Article Number 1271.

Willen L., Basanez M. G., Dvorak V., Veriegh F. B. D., Aboagye F. T., Idun B., Osman M. E., Osei-Atweneboana M. Y., Courteney O., Volf P. (2021). Human immune response against salivary antigens of Simulium damnosus s.l.: A new epidemiological marker for exposure to blackfly bites in onchocerciasis endemic areas. PLoS Neglected Tropical Diseases 15: e0009512.

Kniha E., Dvorak V., Milchram M., Obwaller A. G., Kohsler M., Poeppl W., Antoniou M., Chaskopoulou A., Paronyan L., Stefanovski J., Mooseder G., Volf P., Walochnik J. (2021) Phlebotomus (Adlerius) simici NITZULESCU, 1931: first record in Austria and phylogenetic relationship with other Adlerius species. PARASITES & VECTORS 14: Article Number 20.

Kniha E., Milchram M., Dvorak V., Halada P., Obwaller A. G., Poeppl W., Mooseder G., Volf P., Walochnik J. (2021). Ecology, seasonality and host preferences of Austrian Phlebotomus (Transphlebotomus) mascittii Grassi, 1908, populations. PARASITES & VECTORS 14: Article Number 291.

Diniz J. A., Chaves M. M., Vaselek S., Magalhaes R. D. M., Ricci-Azevedo R., De Carvalho R. V. H., Lorenzon L. B., Ferreira T. R., Zamboni D., Walrad P. B., Volf P., Sacks D. L., Cruz A. K. (2021) Protein methyltransferase 7 deficiency in Leishmania major increases neutrophil associated pathology in murine model. PLOS NEGLECTED TROPICAL DISEASES 15: Article Number e0009230.

Baker N., Catta-Preta C. M. C., Neish R., Sadlova J., Powell B., Alves-Ferreira E. V. C., Geoghegan V., Carnielli J. B. T., Newling K., Hughes C., Vojtkova B., Anand J., Mihut A., Walrad P. B., Wilson L. G., Pitchford J. W., Volf P., Mottram J. C. (2021) Systematic functional analysis of Leishmania protein kinases identifies regulators of differentiation or survival. Nature Communications 12: 1244.

Schwabl P., Boite M. C., Bussotti G., Jacobs A., Andersson B., Moreira O., Freitas-Mesquita A. L., Meyer-Fernandes J. R., Telleria E. L., Traub-Cseko Y., Vaselek S., Lestinova T., Volf P., Morgado F. N., Porrozzi R., Llewellyn M., Spath G. F., Cupolillo E.  (2021) Colonization and genetic diversification processes of Leishmania infantum in the Americas. COMMUNICATIONS BIOLOGY 4: Article Number 139.

Ashwin H., Sadlova J., Vojtkova B., Becvar T., Lypaczewski P., Schwartz E., Greensteed E., Van Boxlaer K., Parin M., Lipinski K. S., Parkash V., Matlashewski G., Layton A. M., Lacey C. J., Jaffe C. L., Volf P., Kay P. M. (2021). Characterization of a new Leishmania major strain for use in a controlled human infection model. Nature Communications 12: 215.

Sloan M. A., Sadlova J., Lestinova T., Sanders M. J., Cotton J. A., Volf P., Ligoxygakis P. (2021) The Phlebotomus papatasi systemic transcriptional response to trypanosomatid-contaminated blood does not differ from the non-infected blood meal. PARASITES & VECTORS 14: Article Number 15.

Becvar T., Vojtkova B., Siriyasatien P., Votypka J. Modry D., Jahn P., Bates P., Carpenter S., Volf P. & Sadlova J. (2021) Experimental transmission of Leishmania (Mundinia) parasites by biting midges (Diptera: Ceratopogonidae). PLoS Pathogens 17(6): e1009654.

Lesiczka P., Hrazdilová K., Majerová K., Fonville M., Sprong H., Hönig V., Hofmannová L., Papežík P., Růžek D., Zurek L., Votýpka J. & Modrý D. (2021). The role of peridomestic animals in the eco-epidemiology of Anaplasma phagocytophilum. Microbial Ecology (https://doi.org/10.1007/s00248-021-01704-z).

Majerová K., Gutiérrez R., Fonville K., Hönig V., Papežík P., Hofmannová L., Lesiczka P. M., Nachum-Biala Y., Růžek D., Sprong H., Harrus S., Modrý D. & Votýpka J. (2021) Hedgehogs and squirrels as hosts of zoonotic Bartonella species. Pathogens 10: 686.

Votýpka J., Petrželková K. J., Brzoňová J., Jirků M., Modrý D. & Lukeš J. (2021) How monoxenous trypanosomatids revealed hidden feeding habits of their tsetse fly hosts. Folia Parasitologica 68: 019.

Belinky F., Ganguly I., Poliakov E., Yurchenko V., Rogozin I. B. Analysis of stop codons within prokaryotic protein-coding genes suggests frequent readthrough events. Int. J. Mol. Sci., 2021, 22: 1876.

Lukeš J., Tesařová M., Yurchenko V., Votýpka J. Characterization of a new cosmopolitan genus of trypanosomatid parasites, Obscuromonas gen. nov. (Blastocrithidiinae subfam. nov.). Eur. J. Protistol., 2021, 79: 125778.

Sádlová J., Podešvová L., Bečvář T., Bianchi C., Gerasimov E. S., Saura A., Glanzová K., Leštinová T., Matveeva N. S., Chmelová L., Mlacovská D., Spitzová T., Vojtková B., Volf P., Yurchenko V., Kraeva N. Catalase impairs Leishmania mexicana development and virulence. Virulence, 2021, 12(1): 852-867.

Charyyeva A., Çetinkaya Ü., Özkan B., Şahin S., Yaprak N., Şahin I., Yurchenko V., Kostygov A. Y. Genetic diversity of Leishmania tropica: unexpectedly complex distribution pattern. Acta Trop., 2021, 218: 105888.

Albanaz A. T. S., Gerasimov E. S., Shaw J. J., Sádlová J., Lukeš J., Volf P., Opperdoes F. R., Kostygov A. Y., Butenko A., Yurchenko V. Genome analysis of Endotrypanum and Porcisia spp., closest phylogenetic relatives of Leishmania, highlights the role of amastins in shaping pathogenicity. Genes. 2021, 12(3): 444.

Gerasimov E. S., Gasparyan A. A., Afonin D. A., Zimmer S. L., Kraeva N., Lukeš J., Yurchenko V., Kolesnikov A. Complete minicircle genome of Leptomonas pyrrhocoris reveals a source of its non-canonical mitochondrial RNA editing events. Nucl. Acids Res., 2021, 49(6): 3354-3370.

Frolov A. O., Kostygov A. Y., Yurchenko V. Development of monoxenous trypanosomatids and phytomonads in insects. Trends Parasitol., 2021, 37(6): 538-551.

Skalický T., Alves J. M. P., Morais A. C., Režnarová J., Butenko A., Lukeš J., Serrano M. G., Buck G. A., Teixeira M. M. G., Camargo E. P., Sanders M., Cotton J. A., Yurchenko V., Kostygov A. Y. Endosymbiont capture, a repeated process of endosymbiont transfer with replacement in trypanosomatids Angomonas spp. Pathogens, 2021, 10: 702.

Konorov E. A., Yurchenko V., Patraman I. V., Lukashev A. N., Oyun N. Y. The effects of genetic drift and genomic selection on differentiation and local adaptation of the introduced populations of Aedes albopictus in southern Russia. Peer J., 2021, 9: e11776.

Barcytė D., Eikrem W., Engesmo A., Seoane S., Wohlmann J., Horák A., Yurchenko T., Eliáš M. Olisthodiscus represents a new class of Ochrophyta. J. Phycol., 2021, 57: 1094-1118.

Tice A. K., Žihala D., Pánek T., Jones R. J., Salomaki E., Nenarokov S., Burki F., Eliáš M., Eme L., Roger A. J., Rokas A., Shen X.-X., Strassert J. F. H., Kolísko M., Brown M. W. PhyloFisher: a phylogenomic package for resolving deep eukaryotic relationships. PLoS Biol., 2021, 19: e3001365.

Larue G. E., Eliáš M., Roy S. W. Expansion and transformation of the minor spliceosomal system in the slime mold Physarum polycephalum. Curr. Biol., 2021, 31: P3125-3131.E4.

Herman E. K., Greninger A., van der Giezen M., Ginger M. L., Ramirez-Macias I., Miller H. C., Morgan M. J., Tsaousis A. D., Velle K., Vargová R., Záhonová K., Najle S. R., MacIntyre G., Muller N., Wittwer M., Zysset-Burri D. C., Eliáš M., Slamovits C., Weirauch M., Fritz-Laylin L., Marciano-Cabral F., Puzon G. J., Walsh T., Chiu C., Dacks J. B. Genomics and transcriptomics yields a systems-level view of the biology of the pathogen Naegleria fowleri. BMC Biol., 2021, 19: 142.

Pyrih J., Žárský V., Fellows D.J., Grosche C., Wloga D., Striepen B, Maier G.U., Tachezy J. 2021. The iron-sulfur scaffold protein HCF101 unveils the complexity of organellar evolution in SAR, Haptista and Cryptista. BMC Evolutionary Biology 21, Article number: 46 (2021)

Žárský V., Klimeš V., Pačes J., Vlček Č, Hradilová M., Beneš V., Nývltová E., Hrdý I., Pyrih J, Mach J., Barlow L., Stairs C.W., Eme L., Hall N., Eliáš M., Dacks BJ, Roger A., Tachezy J. 2021. The Mastigamoeba balamuthi genome and the nature of the free-living ancestor of Entamoeba. Mol. Biol. Evol. doi: 10.1093/molbev/msab020. Online ahead of print. PMID: 33528570, IF 11,062

Bensaoud Ch., Martins L. A., Aounallah H., Hackenberg M., Kotsyfakis M. Emerging roles of non-coding RNAs in vector-borne infections. J Cell Sci (2021) 134 (5): jcs246744. https://doi.org/10.1242/jcs.246744

Villafraz O., Biran M., Pineda E., Plazolles N., Cahoreau E., Ornitz Oliveira Souza R., et al. (2021) Procyclic trypanosomes recycle glucose catabolites and TCA cycle intermediates to stimulate growth in the presence of physiological amounts of proline. PLoS Pathog 17(3): e1009204. https://doi.org/10.1371/journal.ppat.1009204

Kostygov A.Y., Karnkowska A., Votýpka J., Tashyreva D., Maciszewski K., Yurchenko V. & Lukeš J. (2021). Euglenozoa: taxonomy, diversity and ecology, symbioses and viruses. Open Biology 11: 200407. 

Horváthová L., Žárský V., Pánek T., Derelle R., Pyrih J., Motyčková A., Klápšťová V., Vinopalová M., Marková L., Voleman L., Klimeš V., Petrů M., Vaitová Z., Čepička I., Hryzáková K., Harant K., Gray M. W., Chami M., Guilvout I., Francetic O., Franz Lang B., Vlček Č., Tsaousis A.D., Eliáš M., Doležal P. Analysis of diverse eukaryotes suggests the existence of an ancestral mitochondrial apparatus derived from the bacterial type II secretion system. Nat Commun. 2021 May 19;12(1):2947. doi: 10.1038/s41467-021-23046-7.

Rout S., Oeljeklaus S., Makki A., Tachezy J., Warscheid B., Schneider A. Determinism and contingencies shaped the evolution of mitochondrial protein import. Proceedings of the National Academy of Sciences Feb 2021, 118 (6) e2017774118; DOI: 10.1073/pnas.2017774118

Hierro-Yap C., Šubrtová K., Gahura O., Panicucci B., Dewar C., Chinopoulos Ch., Schnaufer A., Zíková A. Bioenergetic consequences of FoF1–ATP synthase/ATPase deficiency in two life cycle stages of Trypanosoma brucei, Journal of Biological Chemistry, Volume 296, 2021 , ISSN 0021-9258, https://doi.org/10.1016/j.jbc.2021.100357.

Procházková M., Füzik T., Grybchuk D., Luca Falginell F., Podešvová L., Yurchenko V., Vácha R., Plevka P. Capsid structure of Leishmania RNA Virus 1. Journal of Virology. Jan 2021, 95 (3) e01957-20, doi:10.1128/JVI.01957-20

Čermáková, P., Maďarová, A., Baráth, P., Bellová, J., Yurchenko, V., & Horváth, A. (2021). Differences in mitochondrial NADH dehydrogenase activities in trypanosomatids. Parasitology, 1-10. doi:10.1017/S0031182020002425 

Gahura O., Hierro Yap C., Zíková A. (2021). Redesigned and reversed: architectural and functional oddities of the trypanosomal ATP synthase. Parasitology. 8:1-41

Tobiasson V., Gahura O., Aibara S., Baradaran R., Zíková A., Amunts A. (2021). Interconnected assembly factors regulate the biogenesis of mitoribosomal large subunit. EMBO J.

Opperdoes F. R., Butenko A., Zakharova A., Gerasimov E. S., Zimmer S. L., Lukeš J., & Yurchenko V. (2021). The remarkable metabolism of Vickermania ingenoplastis: Genomic predictions. Pathogens, 10(1), 68. https://doi.org/10.3390/pathogens10010068

Lukeš J., Kaur B., & Speijer D. (2021). RNA editing in mitochondria and plastids: weird and widespread. Trends in genetics : TIG, 37(2), 99–102. https://doi.org/10.1016/j.tig.2020.10.004

Butenko A., Hammond M., Field M. C., Ginger M. L., Yurchenko V., & Lukeš J. (2021). Reductionist pathways for parasitism in Euglenozoans? Expanded datasets provide new insights. Trends in parasitology, 37(2), 100–116. https://doi.org/10.1016/j.pt.2020.10.001

Mahmood S., Sima R., Urbanova V., Trentelman J. J. A., Krezdorn N., Winter P., Kopacek P., Hovius J. W., Hajdusek O. (2021). Identification of tick Ixodes ricinus midgut genes differentially expressed during the transmission of Borrelia afzelii spirochetes using a transcriptomic approach. Front Immunol. 11:612412. doi: 10.3389/fimmu.2020.612412.

Kozelková T., Doležel D., Grunclová L., Kučera M., Perner J., Kopáček P. (2021) Functional characterization of the insulin signaling pathway in the hard tick Ixodes ricinus. Ticks and Tick-borne Diseases 12  101694, https://doi.org/10.1016/j.ttbdis.2021.101694

Klouwens M. J., Trentelman J. J., Ersoz J. I., Nieves Marques Porto F., Sima R., Hajdusek O., Thakur M., Pal U., Hovius J. W. (2021) Investigating BB0405 as a novel Borrelia afzelii vaccination candidate in Lyme borreliosis. Sci Rep. 11(1):4775. doi: 10.1038/s41598-021-84130-y.

Dorrah M., Bensaoud C., Mohamed A. A., Sojka D., Bassal T. T. M., Kotsyfakis M. (2021) Comparison of the hemolysis machinery in two evolutionarily distant blood-feeding arthropod vectors of human diseases. PLoS Negl Trop Dis 15(2): e0009151. https://doi.org/10.1371/journal.pntd.0009151

Ahmad P., Bensaoud C., Mekki I., Rehman M. U., Kotsyfakis M. (2021). Long non-coding RNAs and their potential roles in the vector-host-pathogen triad.  Life (Basel) 11(1):56. doi: 10.3390/life11010056. 

Kotabova E., Malych R., Pierella Karlusich J. J., Kazamia E., Eichner M., Mach J., Lesuisse E., Bowler C., Prášil O., Sutak R. Complex response of the chlorarachniophyte Bigelowiella natans to iron availability. mSystems. 2021

Füssy Z., Vinopalová M., Treitli S. C., Pánek T., Smejkalová P., Čepička I., Doležal P., Hampl V. Retortamonads from vertebrate hosts share features of anaerobic metabolism and pre-adaptations to parasitism with diplomonads. Parasitol Int. 2021 Feb 21;82:102308. doi: 10.1016/j.parint.2021.102308.

2020

Alama-Bermejo G., Meyer E., Atkinson S. D., Holzer A. S., Wiśniewska M. M., Kolísko M., Bartholomew J. L. Transcriptome-wide comparisons and virulence gene polymorphisms of host-associated genotypes of the Cnidarian parasite Ceratonova shasta in salmonids. Genome Biology and Evolution. Volume 12, Issue 8. August 2020. Pages 1258–1276 https://doi.org/10.1093/gbe/evaa109

Dixit S., Alfonzo J. D., Lukeš J. (2020). RNA-Binding proteins and their targets in Trypanosoma brucei: Single nucleotide resolution using iCLIP and iCLAP. In: Michels, P., Ginger, M., Zilberstein, D. (eds) Trypanosomatids. Methods in Molecular Biology, vol 2116. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-0294-2_19

Žihala D., Salamonová J., Eliáš M.  Evolution of the genetic code in the mitochondria of Labyrinthulea (Stramenopiles), Molecular Phylogenetics and Evolution, Volume 152, 2020, ISSN 1055-7903, https://doi.org/10.1016/j.ympev.2020.106908

Ravoitytė B., Lukša J., Yurchenko V., Serva S., Servienė E. Saccharomyces paradoxus transcriptional alterations in cells of distinct phenotype and viral dsRNA content. Microorganisms 2020, 8, 1902. https://doi.org/10.3390/microorganisms8121902

Kostygov A.Y., Frolov A.O., Malysheva M.N. et al. Vickermania gen. nov., trypanosomatids that use two joined flagella to resist midgut peristaltic flow within the fly host. BMC Biol 18, 187 (2020). https://doi.org/10.1186/s12915-020-00916-y

Durante I. M., Butenko A., Rašková V., Charyyeva A., Svobodová M., Yurchenko V., Hashimi H., Lukeš J. Large-scale phylogenetic analysis of trypanosomatid adenylate cyclases reveals associations with extracellular lifestyle and host–pathogen interplay. Genome Biology and Evolution, Volume 12, Issue 12, December 2020, Pages 2403–2416, https://doi.org/10.1093/gbe/evaa226

Perner J., Helm D., Haberkant P. et al. The central role of salivary metalloproteases in host acquired resistance to tick feeding. Frontiers in Cellular and Infection Microbiology 10, 703 (2020). https://www.frontiersin.org/article/10.3389/fcimb.2020.563349

Mateos-Hernandéz L., Defaye B., Vancová M. et al. Cholinergic axons regulate type I acini in salivary glands of Ixodes ricinus and Ixodes scapularis ticks. Sci Rep 10, 16054 (2020). https://doi.org/10.1038/s41598-020-73077-1

Salomaki E.D., Eme L., Brown M.W. et al. Releasing uncurated datasets is essential for reproducible phylogenomics. Nat Ecol Evol 4, 1435–1437 (2020). https://doi.org/10.1038/s41559-020-01296-w

Miroslav Oborník. Photoparasitism as an intermediate state in the evolution of apicomlexan parasites. Trends in Parasitology. Volume 36, Issue 9. September 2020. Pages 727-734. https://doi.org/10.1016/j.pt.2020.06.002

Joseph T Smith Jr, Eva Doleželová, Brianna Tylec, Jonathan E Bard, Runpu Chen, Yijun Sun, Alena Zíková, Laurie K Read. Developmental regulation of edited CYb COIII mitochondrial mRNAs is achieved by distinct mechanisms in Trypanosoma brucei. Nucleic Acids Reasearch. Volume 48, Issue 15. 04 September 2020. Pages 8704–8723. https://doi.org/10.1093/nar/gkaa641

Serricchio M., Hierro-Yap C., Schädeli D., Ben Hamidane H., Hemphill A., Graumann J., Zíková A., Bütikofer P. (2020). Depletion of cardiolipin induces major changes in energy metabolism in Trypanosoma brucei bloodstream forms. FASEB J. 35:e21176.

Horák A., Allen A.E., Oborník M. (2020) Common origin of ornithine–urea cycle in opisthokonts and stramenopiles. Scientific Reports 10, 16687. DOI: 10.1038/s41598-020-73715-8

Trentelman J. J. A., Sima R., Krezdorn N., Tomás-Cortázar J., Barriales D., Takumi K., Butler J. M., Sprong H., Klouwens M. J., Urbanova V., Mahmood S., Winter P., Kopacek P., Anguita J., Hajdusek O., Hovius J. W. (2020). A combined transcriptomic approach to identify candidates for an anti-tick vaccine blocking B. afzelii transmission. Sci Rep. 10 (1):20061. doi: 10.1038/s41598-020-76268-y.

Martins L. A., Bensaoud C., Kotál J., Chmelař J., Kotsyfakis M. (2020) Tick salivary gland transcriptomics and proteomics. Parasite Immunol. e12807. doi:10.1111/pim.12807. 

Bensaoud C., Martins L. A., Aounallah H., Hackenberg M., Kotsyfakis M. (2020) Emerging roles of non-coding RNAs in vector-borne infections.  J Cell Sci. 134(5):jcs246744. doi: 10.1242/jcs.246744. 

Aounallah H., Bensaoud C., M'ghirbi Y., Faria F., Chmelar J. I., Kotsyfakis M. (2020). Tick salivary compounds for targeted immunomodulatory therapy.  Front Immunol.11:583845. doi: 10.3389/fimmu.2020.583845. 

Lhotská Z., Jirků M., Hložková O., Brožová K., Jirsová D., Stensvold C. R., Kolísko M., Jirků Pomajbíková K. (2020) A study on the prevalence and subtype diversity of the intestinal protist Blastocystis sp. in a gut-healthy human population in the Czech Republic. Front Cell Infect Microbiol. 10:544335. doi: 10.3389/fcimb.2020.544335.

Kolisko M., Flegontova O., Karnkowska A., Lax G., Maritz J. M., Pánek T., Táborský P., Carlton J. M., Čepička I., Horák A., Lukeš J., Simpson A. G. B., Tai V. (2020) EukRef-excavates: seven curated SSU ribosomal RNA gene databases. Database 2020:baaa080. doi: 10.1093/database/baaa080.

Grechnikova M., Ženíšková K., Malych R., Mach J., Sutak R. Copper detoxification machinery of the brain-eating amoeba Naegleria fowleri involves copper-translocating ATPase and the antioxidant system. Int J Parasitol Drugs Drug Resist. 2020

Sutak R., Camadro J. M., Lesuisse E. Iron uptake mechanisms in marine phytoplankton. Front Microbiol. 2020

Füssy Z., Záhonová K., Tomčala A., Krajčovič J., Yurchenko V., Oborník M., Eliáš M. The cryptic plastid of Euglena longa defines a new type of nonphotosynthetic plastid organelle. mSphere. 2020 Oct 21;5(5):e00675-20. doi: 10.1128/mSphere.00675-20. PMID: 33087518; PMCID: PMC7580956.

Tomečková L., Tomčala A., Oborník M., Hampl V. The lipid composition of Euglena gracilis middle plastid membrane resembles that of primary plastid envelopes. Plant Physiol. 2020 Dec;184(4):2052-2063. doi: 10.1104/pp.20.00505. Epub 2020 Oct 2. PMID: 33008834; PMCID: PMC7723114.

Vojtkova B., Spitzova T., Votypka J., Lestinova T., Kominkova I., Hajkova M., Santos-Mateus D., Miles M. A., Volf P., Sadlova J. (2020) Central Asian rodents as model animals for Leishmania major and Leishmania donovani research. MICROORGANISMS 8: Article Number 1440.

Sumova P., Polanska N., Lestinova T., Spitzova T., Kalouskova B., Vanek O., Volf P., Rohousova I. (2020) Phlebotomus perniciosus recombinant salivary proteins polarize murine macrophages toward the anti-inflammatory phenotype. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY 10: Article Number 427.

Nacif-Pimenta R., Pinto L. C., Volfova V., Volf P., Pimenta P. F. P., Secundino N. F. C. (2020) Conserved and distinct morphological aspects of the salivary glands of sand fly vectors of leishmaniasis: an anatomical and ultrastructural study. PARASITES & VECTORS 13: Article Number 441.

Kniha E., Dvorak V., Halada P., Milchram M., Obwaller A. G., Kuhls K., Schlegel S., Kohsler M., Poeppl W., Bakran-Lebl K., Fuehrer H. P., Volfova V., Mooseder G., Ivovic V., Volf P., Walochnik J. (2020) Integrative approach to Phlebotomus mascittii Grassi, 1908: First record in Vienna with new morphological and molecular insights. PATHOGENS 9: Article Number 1032.

Halliday C., Yanas R., Catta-Preta C. M. C., Moreira-Leite F., Myskova J., Pruzinova K., Volf P., Mottram J., Sunter J. D. (2020) Role for the flagellum attachment zone in Leishmania anterior cell tip morphogenesis. PLOS PATHOGENS 16: e 1008494.

Dvorak V., Tsirigotakis N., Pavlou C., Dokianakis E., Akhoundi M., Halada P., Volf P., Depaquit J., Antoniou M. (2020) Sand fly fauna of Crete and the description of Phlebotomus (Adlerius) creticus n. sp. (Diptera: Psychodidae). PARASITES & VECTORS 13: Article Number 547.

Majerová K., Hönig V., Houda M., Papežík P., Fonville M., Sprong H., Rudenko N., Golovchenko M., Černá Bolfíková B., Hulva P., Růžek D., Hofmannová L., Votýpka J. & Modrý D. (2020) Hedgehogs, squirrels, and blackbirds as sentinel hosts for active surveillance of Borrelia miyamotoi and Borrelia burgdorferi complex in urban and rural environments. MICROORGANISMS 8(12): 1908. 

Vechtova P., Fussy Z., Cegan R. et al. Catalogue of stage-specific transcripts in Ixodes ricinus and their potential functions during the tick life-cycle. Parasites Vectors 13, 311 (2020). https://doi.org/10.1186/s13071-020-04173-4

Tien Le, Žárský V., Nývltová E., Rada P., Harant K., Vancová M., Verner Z., Hrdý I., Tachezy J. (2020) Anaerobic peroxisomes in Mastigamoeba balamuthi. Proceedings of the National Academy of Sciences, 117 (4) 2065-2075; DOI: 10.1073/pnas.1909755117

Mach J., Sutak R. Iron in parasitic protists - from uptake to storage and where we can interfere. Metallomics. 2020

Sarink M. J., Tielens A. G. M., Verbon A., Sutak R., van Hellemond J. J. Inhibition of fatty acid oxidation as a new target to treat Primary Amoebic Meningoencephalitis. Antimicrob Agents Chemother. 2020

Arbon D., Ženíšková K., Mach J., Grechnikova M., Malych R., Talacko P., Sutak R. Adaptive iron utilization compensates for the lack of an inducible uptake system in Naegleria fowleri and represents a potential target for therapeutic intervention. PLoS Negl Trop Dis. 2020

Najdrová V., Stairs C., Voleman L., Vinopalova M., Doležal P. The evolution of the Puf superfamily of proteins across the tree of eukaryotes. BMC Biology 2020 https://doi.org/10.1186/s12915-020-00814-3

Majer M., Macháček T., Súkeníková L., Hrdý J., Horák P. (2020): The peripheral immune response of mice infected with a neuropathogenic schistosome. Parasite Immunology 42: e12710. DOI: 10.1111/pim.12710 [IF2019=2.054]

Macháček T., Šmídová B., Pankrác J., Majer M., Bulantová J., Horák P. (2020): Nitric oxide debilitates the neuropathogenic schistosome Trichobilharzia regenti in mice, partly by inhibiting its vital peptidases. Parasites & Vectors 13: 426. DOI: 10.1186/s13071-020-04279-9 [IF2019=2.824]

Harada R., Hirakawa Y., Yabuki A., Kashiyama Y., Maruyama M., Onuma R., Soukal P., Miyagishima S., Hampl V., Tanifuji G., Inagaki Y. Inventory and evolution of mitochondrion-localized family a DNA polymerases in Euglenozoa. Pathogens. 2020 Apr 1;9(4):257. doi: 10.3390/pathogens9040257. PMID: 32244644; PMCID: PMC7238167.

Vaselek S., Prudhomme J., Myskova J., Lestinova T., Spitzova T., Banuls A. L., Volf P. (2020) Comparative study of Promastigote- and Amastigote-initiated infection of Leishmania infantum (Kinetoplastida: Trypanosomatidae) in Phlebotomus perniciosus (Diptera: Psychodidae) conducted in different biosafety level laboratories. JOURNAL OF MEDICAL ENTOMOLOGY 57: 601-607.

Hendrickx S., Van Bockstal L., Aslan H., Sadlova J., Maes L., Volf P., Caljon G. (2020) Transmission potential of paromomycin-resistant Leishmania infantum and Leishmania donovani. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 75: 951-957.

Sadlova J., Vojtkova B., Becvar T., Lestinova T., Spitzova T., Bates P., Volf P. (2020) Host competence of the African rodents Arvicanthis neumanni, A. niloticus and Mastomys natalensis for Leishmania donovani from Ethiopia and L. (Mundinia) sp. from Ghana. INTERNATIONAL JOURNAL FOR PARASITOLOGY-PARASITES AND WILDLIFE 11: 40-45.

Cotton J. A., Durrant C., Franssen S. U., Gelanew T., Hailu A., Mateus D., Sanders M. J., Berriman M., Volf P., Miles M. A., Yeo M. (2020) Genomic analysis of natural intra-specific hybrids among Ethiopian isolates of Leishmania donovani. PLOS NEGLECTED TROPICAL DISEASES 14: e0007143.

Becvar T., Siriyasatien P., Bates P., Volf P., Sadlova J., (2020) Development of Leishmania (Mundinia) in guinea pigs. PARASITES & VECTORS 13: DOI: 10.1186/s13071-020-04039-9

Maia C., Cristovao J., Pereira A., Kostalova T., Lestinova T., Sumova P., Volf P., Campino L. (2020) Monitoring Leishmania infection and exposure to Phlebotomus perniciosus using minimal and non-invasive canine samples. PARASITES & VECTORS 13: DOI: 10.1186/s13071-020-3993-7

Burnham A. C., Ordeix L., Alcover M. M., Martinez-Orellana P., Montserrat-Sangra S., Willen L., Spitzova T., Volf P., Solano-Gallego L. (2020) Exploring the relationship between susceptibility to canine leishmaniosis and anti-Phlebotomus perniciosus saliva antibodies in Ibizan hounds and dogs of other breeds in Mallorca, Spain. PARASITES & VECTORS 13: DOI: 10.1186/s13071-020-3992-8

Spitzova T., Sumova P., Volfova V., Polanska N., Poctova L., Volf P. (2020) Interactions between host biogenic amines and sand fly salivary yellow-related proteins. PARASITES & VECTORS 13: DOI: 10.1186/s13071-020-04105-2

Van Bockstal L., Bulte D., Hendrickx S., Sadlova J., Volf P., Maes L., Caljon G. (2020) Impact of clinically acquired miltefosine resistance by Leishmania infantum on mouse and sand fly infection. INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE 13: 16-21.

Hrazdilová K., Rybářová M., Široký P., Votýpka J., Zintl A., Burgess H., Steinbauer V., Žákovčík V. & Modrý D. (2020) Diversity of Babesia spp. in cervid ungulates based on the 18S rDNA and cytochrome c oxidase subunit I phylogenies. Infection, Genetics and Evolution 77: 104060.

Votýpka J., Kment P., Yurchenko V. & Lukeš J. (2020) Endangered monoxenous trypanosomatid parasites: a lesson from island biogeography. Biodiversity and Conservation. DOI 10.1007/s10531-020-02041-2

Tomčala A., Michálek J., Schneedorferová I., Füssy Z., Gruber A., Vancová M., Oborník M. Fatty acid biosynthesis in chromerids. Biomolecules 2020, 10, 1102. https://doi.org/10.3390/biom10081102

Thomas S. Corrigan, Leilani M. Lotti Diaz, Sarah E. Border, Steven C. Ratigan, Kayla Q. Kasper, Daniel Sojka, Pavla Fajtova, Conor R. Caffrey, Guy S. Salvesen, Craig A. McElroy, Christopher M. Hadad & Özlem Doğan Ekici (2020) Design, synthesis, and in vitro evaluation of aza-peptide aldehydes and ketones as novel and selective protease inhibitors, Journal of Enzyme Inhibition and Medicinal Chemistry, 35:1, 1387-1402, DOI: 10.1080/14756366.2020.1781107

Pyrih J., Rašková V., Škodová-Sveráková I., Pánek T., Lukeš J. (2020) ZapE/Afg1 interacts with Oxa1 and its depletion causes a multifaceted phenotype. PLoS ONE 15(6): e0234918. https://doi.org/10.1371/journal.pone.0234918

Faktorová D., Kaur B., Valach M., Graf L., Benz C., Burger G., Lukeš J. (2020) Targeted integration by homologous recombination enables in situ tagging and replacement of genes in the marine microeukaryote Diplonema papillatum. Environ Microbiol, 22: 3660-3670. doi:10.1111/1462-2920.15130

Doleželová E., Kunzová M., Dejung M., Levin M., Panicucci B., Regnault C., et al. (2020) Cell-based and multi-omics profiling reveals dynamic metabolic repurposing of mitochondria to drive developmental progression of Trypanosoma brucei. PLoS Biol 18(6): e3000741. https://doi.org/10.1371/journal.pbio.3000741

Rotterová J., Salomaki E., Pánek T., Bourland W., Žihala D., Táborský P., Edgcomb V. P., Beinart R. A., Kolísko M., Čepička I. (2020) Genomics of new ciliate lineages provides insight into the evolution of obligate anaerobiosis. Current Biology, 30 (11), 2037-2050.e5 https://doi.org/10.1016/j.cub.2020.03.064

Speijer D., Hammond M., Lukeš J. (2020) Comparing early eukaryotic integration of mitochondria and chloroplasts in the light of internal ROS challenges: Timing is of the essence. mBio, 11 (3) e00955-20; DOI: 10.1128/mBio.00955-20

Guizzo M. G., Neupane S., Kucera M., Perner J., Frantová H., da Silva Vaz I., Oliveira P. L. de, Kopacek P., Zurek L. (2020) Poor unstable midgut microbiome of hard ticks contrasts with abundant and stable monospecific microbiome in ovaries. Frontiers in Cellular and Infection Microbiology, 10, 211, https://doi.org/10.3389/fcimb.2020.00211

Zoltner et al. (2020) Suramin exposure alters cellular metabolism and mitochondrial energy production in African trypanosomes. The Journal of Biological Chemistry, 295, 8331-8347 https://doi.org/10.1074/jbc.RA120.012355

Faktorová D. et al. Genetic tool development in marine protists: emerging model organisms for experimental cell biology. Nat Methods. 2020 May;17(5):481-494. doi:10.1038/s41592-020-0796-x. Epub 2020 Apr 6. Erratum in: Nat Methods. 2020 Apr 15;: PMID: 32251396; PMCID: PMC7200600.

Michael J Hammond, Anna Nenarokova, Anzhelika Butenko, Martin Zoltner, Eva Lacová Dobáková, Mark C Field, Julius Lukeš. A uniquely complex mitochondrial proteome from Euglena gracilis. Molecular Biology and Evolution. Volume 37, Issue 8. August 2020. Pages 2173–2191. https://doi.org/10.1093/molbev/msaa061

Aphasizheva I. et al. (2020) Lexis and grammar of mitochondrial RNA processing in Trypanosomes. Trends in Parasitology: 36 (4), 337-355 https://doi.org/10.1016/j.pt.2020.01.006

Lukeš J., Votýpka J. (2020) Field isolation and cultivation of Trypanosomatids from insects. In: Michels P., Ginger M., Zilberstein D. (eds) Trypanosomatids. Methods in Molecular Biology, vol 2116. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-0294-2_1

George E., Husník F., Tashyreva D., Prokopchuk G., Horák A., Kwong W. K., Lukeš J., Keeling P. J. (2020) Highly reduced genomes of protist endosymbionts show evolutionary convergence. Current Biology: 30 (5), 925-933.e3 https://doi.org/10.1016/j.cub.2019.12.070

Chambouvet A., Smilansky V., Jirků M., Isidoro-Ayza M., Itoïz S., Derelle E., et al. (2020) Diverse alveolate infections of tadpoles, a new threat to frogs? PLoS Pathog 16(2): e1008107. https://doi.org/10.1371/journal.ppat.1008107

Škodová-Sveráková I., Prokopchuk G., Peña-Diaz P., Záhonová K., Moos M., Horváth A., Šimek P., Lukeš J. Unique dynamics of paramylon storage in the marine euglenozoan Diplonema papillatum, Protist, Volume 171, Issue 2, April 2020, https://doi.org/10.1016/j.protis.2020.125717

Kaur B., Záhonová K., Valach M., Faktorová D., Prokopchuk G., Burger G., Lukeš J. Gene fragmentation and RNA editing without borders: eccentric mitochondrial genomes of diplonemids, Nucleic Acids Research, Volume 48, Issue 5, 18 March 2020, Pages 2694–2708, https://doi.org/10.1093/nar/gkz1215

Rogozin I. B., Charyyeva A., Sidorenko I. A., Babenko V. N., Yurchenko, V. Frequent recombination events in Leishmania donovani: Mining population data. Pathogens 2020, 9, 572. https://doi.org/10.3390/pathogens9070572

Škodová-Sveráková I., Záhonová K., Bučková B., Füssy Z., Yurchenko V., Lukeš J. Catalase and ascorbate peroxidase in euglenozoan protists. Pathogens 2020, 9, 317. https://doi.org/10.3390/pathogens9040317

Polanska N., Ishemgulova A., Volfova, V., Flegontov P., Votypka J., Yurchenko V., Volf, P. (2020) Sergentomyia schwetzi: Salivary gland transcriptome, proteome and enzymatic activities in two lineages adapted to different blood sources. PLOS ONE 15: e0230537

Pánek T., Eliáš M., Vancová M., Lukeš J., Hashimi H. (2020) Returning to the fold for lessons in mitochondrial crista diversity and evolution. Current Biology, 30 (10) R575-R588; https://doi.org/10.1016/j.cub.2020.02.053

Alexandre J., Sadlova J., Lestinova T. et al. Experimental infections and co-infections with Leishmania braziliensis and Leishmania infantum in two sand fly species, Lutzomyia migonei and Lutzomyia longipalpis. Sci Rep 10, 3566 (2020). https://doi.org/10.1038/s41598-020-60600-7

Konvalinka T., Pánek T., Kováčová B., Horváth A. (2020) Orientation of FtsH protease homologs in Trypanosoma brucei inner mitochondrial membrane and its evolutionary implications. Molecular and Biochemical parasitology, 238; https://doi.org/10.1016/j.molbiopara.2020.111282

Ganyukova A. I., Frolov A. O., Malysheva M. N., Spodareva V. V., Yurchenko V., Kostygov A. Y. 2020: A novel endosymbiont-containing trypanosomatid Phytomonas borealis sp. n. from the predatory bug Picromerus bidens (Heteroptera: Pentatomidae). Folia Parasitol. 67: 004.

Butenko A., Opperdoes F. R., Flegontova O., Horák A., Hampl V., Keeling P., Gawryluk R. M. R., Tikhonenkov D., Flegontov P., Lukeš J. Evolution of metabolic capabilities and molecular features of diplonemids, kinetoplastids, and euglenids. BMC Biol. 2020 Mar 2;18(1):23. doi: 10.1186/s12915-020-0754-1. PMID: 32122335; PMCID: PMC7052976.

Gray M.W., Burger G., Derelle R. et al. The draft nuclear genome sequence and predicted mitochondrial proteome of Andalucia godoyi, a protist with the most gene-rich and bacteria-like mitochondrial genome. BMC Biol 18, 22 (2020). https://doi.org/10.1186/s12915-020-0741-6

Frolov A. O., Malysheva M. N., Ganyukova A. I., Spodareva V. V., Králová J., Yurchenko V., Kostygov A. Y. (2020) If host is refractory, insistent parasite goes berserk: trypanosomatid Blastocrithidia raabei in the true bug Coreus marginatus. PLOS One 15:e0227832.

Dvořáková H., Leontovyč R., Macháček T., O'Donoghue A. J., Šedo O., Zdráhal Z., Craik C. S., Caffrey C. R., Horák P., Mikeš L. (2020): Isoforms of cathepsin B1 in neurotropic schistosomula of Trichobilharzia regenti differ in substrate preferences and a highly expressed catalytically inactive paralog binds cystatin. Frontiers in Cellular and Infection Microbiology 10: 66. DOI: 10.3389/fcimb.2020.00066 [IF2018=3.518]

Skála V., Walker A. J., Horák P. (2020): Snail defence responses to parasite infection: the Lymnaea stagnalis-Trichobilharzia szidati model. Developmental and Comparative Immunology 102: 103464. DOI: 10.1016/j.dci.2019.103464 [IF2018=3.119]

d’Avila-Levy C. M., Bearzatto B., Ambroise J., Helaers R., Butenko A., Yurchenko V., Morelli K. A., Santos H. C. G., Brouillard P., Grellier P., Gala J. L., Vikkula M. (2020) First draft genome of the trypanosomatid Herpetomonas muscarum ingenoplastis through MinION Oxford Nanopore technology and Illumina sequencing. Tropical Medicine and Infectious Disease 5:25.

Gerasimov E., Zamyatnina K., Matveeva N., Rudenskaya Y., Kraeva N., Kolesnikov A. A., Yurchenko V. (2020) Common structural patterns in the maxicircle divergent region of Trypanosomatidae. Pathogens 9:100.

Podešvová L., Leštinová T., Horáková E., Lukeš J., Volf P., Yurchenko V. (2020) Suicidal Leishmania. Pathogens 9:79. DOI: 10.3390/pathogens9020079

Grybchuk N., Macedo D. H., Kleschenko Y., Kraeva N., Lukashev A. N., Bates P. A., Kulich P., Leštinová T., Volf P., Kostygov A. Y., Yurchenko V. (2020) The first non-LRV RNA virus in Leishmania. Viruses 12:E168.

Novák Vanclová A. M. G., Zoltner M., Kelly S., Soukal P., Záhonová K., Füssy Z., Ebenezer T. E., Lacová Dobáková E., Eliáš M., Lukeš J., Field M. C., Hampl V. Metabolic quirks and the colourful history of the Euglena gracilis secondary plastid. New Phytol. 2020 Feb;225(4):1578-1592. doi: 10.1111/nph.16237. Epub 2019 Nov 4. PubMed PMID: 31580486.

Martins L. A., Kotal J., Bensaoud C., Chmelar J. & Kotsyfakis M. Small protease inhibitors in tick saliva and salivary glands and their role in tick-host-pathogen interactions. Biochimica et biophysica acta. Proteins and proteomics 1868, 140336, doi:10.1016/j.bbapap.2019.140336 (2020).

Horáková E., Faktorová D., Kraeva N., Kaur B., Van Den Abbeele J., Yurchenko V., Lukeš J. (2020) Catalase compromises the development of the insect and mammalian stages of Trypanosoma brucei. FEBS Journal, in press (doi: 10.1111/febs.15083).

2019

Ježek J., Votýpka J., Brzoňová J. & Oboňa J. (2019) Horse flies (Diptera: Tabanidae) collected in Central African Republic, Gabon and Liberia with comments on their updated distribution. Acta Musei Silesiae, Scientiae Naturales 68: 263–274.

Eichenberger C., Oeljeklaus S., Bruggisser J., Mani J. , Haenni B. , Kaurov I., Niemann M. , Zuber B. , Lukeš J., Hashimi H., Warscheid B., Schimanski B., Schneider A. (2019) The highly diverged trypanosomal MICOS complex is organized in a nonessential integral membrane and an essential peripheral module Molecular Microbiology 12: 1731–1743. DOI: 10.1111/mmi.14389

Voleman L., Doležal P. Mitochondrial dynamics in parasitic protists. PLoS Pathog. 2019 Nov 21;15(11):e1008008. doi: 10.1371/journal.ppat.1008008. eCollection 2019 Nov. Review.

He C. Y., Singh A., Yurchenko V. (2019). Cell cycle-dependent flagellar disassembly in a firebug trypanosomatid Leptomonas pyrrhocoris. mBio 10:e02424-19.

Žihala D., Eliáš M. (2019). Evolution and unprecedented variants of the mitochondrial genetic code in a lineage of green algae. Genome Biology and Evolution 11:2992-3007.

Gerasimov E., Zemp N., Schmid-Hempel R., Schmid-Hempel P., Yurchenko V. (2019). Genomic variation among strains of Crithidia bombi and C. expoeki. mSphere 4:e00482-19.

Lukešová S., Karlicki M., Tomečková Hadariová L., Szabová J., Karnkowska A., Hampl V. Analyses of environmental sequences and two regions of chloroplast genomes revealed the presence of new clades of photosynthetic euglenids in marine environments. Environ Microbiol Rep. 2020 Feb;12(1):78-91. doi: 10.1111/1758-2229.12817. Epub 2019 Dec 26. PubMed PMID: 31845515.

Beneke T., Demay F., Hookway E., Ashman N., Jeffery H., Smith J., Valli J., Becvar T., Myskova J., Lestinova T., Shafiq S., Sadlova J., Volf P., Wheeler R. J., Gluenz E. (2019). Genetic dissection of a Leishmania flagellar proteome demonstrates requirement for directional motility in sand fly infections. Plos Pathogens 15: e1007828. 

Pereira A., Ayhan N., Cristovao J. M., Vilhena H., Martins A., Cachola P., Henriques J., Coimbra M., Catarino A., Lestinova T., Spitzova T., Volf P., Campino L., Charrel R., Maia C. (2019). Antibody response to Toscana Virus and Sandfly Fever Sicilian Virus in cats naturally exposed to Phlebotomine sand fly bites in Portugal. Microorganisms 7:  Article Number 339.  

Van Bockstal L., Sadlova J., Suau H. A., Hendrickx S., Meneses C., Kamhawi S., Volf P., Maes L., Caljon G. (2019). Impaired development of a miltefosine-resistant Leishmania infantum strain in the sand fly vectors Phlebotomus perniciosus and Lutzomyia longipalpis. International Journal for Parasitology – Drugs and Drug Resistance 11, SI: 1-7.

Seblova V., Dujardin J. C., Rijal S., Domagalska M. A., Volf P. (2019). ISC1, a new Leishmania donovani population emerging in the Indian sub-continent: Vector competence of Phlebotomus argentipes.  Infection Genetics and Evolution 76:  Article Number 104073.  

Butenko A. ,Kostygov A. Y., Sadlova J., Kleschenko Y., Becvar T., Podesvova L., Macedo D. H., Zihala D., Lukes J., Bates P. A., Volf P., Opperdoes F. R., Yurchenko V. (2019) Comparative genomics of Leishmania (Mundinia). BMC Genomics 20: Article Number 726.

Hlavackova K., Dvorak V., Chaskopoulou A., Volf P., Halada P. (2019). A novel MALDI-TOF MS-based method for blood meal identification in insect vectors: A proof of concept study on phlebotomine sand flies. PLoS Neglected Tropical Diseases 13: e0007669.

Willen L., Lestinova T., Kalouskova B., Sumova P., Spitzova T., Velez R., Domenech E., Vanek O., Gallego M., Mertens P., Volf P. (2019). Field study of the improved rapid sand fly exposure test in areas endemic for canine leishmaniasis. PLoS Neglected Tropical Diseases 13: e0007832.

Giraud E., Svobodova M., Muller I., Volf P., Rogers M. E. (2019) Promastigote secretory gel from natural and unnatural sand fly vectors exacerbate Leishmania major and Leishmania tropica cutaneous leishmaniasis in mice. Parasitology 146: 1796-1802. 

Sumova P., Sima M., Kalouskova B., Polanska N., Vanek O., Oliveira F., Valenzuela J. G., Volf P. (2019). Amine-binding properties of salivary yellow-related proteins in phlebotomine sand flies. Insect Biochemistry and Molecular Biology 115: 103245.

Vaselek S., Volf P. (2019). Experimental infection of Phlebotomus perniciosus and Phlebotomus tobbi with different Leishmania tropica strains. International Journal for Parasitology 49: 831-835.

Kraeva N., Leštinová T., Ishemgulova A., Majerová K., Butenko A., Vaselek S., Bespyatykh J., Charyyeva A., Spitzová T., Kostygov A.Y., Lukeš J., Volf P., Votýpka J. & Yurchenko V. (2019) LmxM.22.0250-encoded dual specificity protein/lipid phosphatase impairs Leishmania mexicana virulence in vitro. Pathogens 8: 241.

Hönig V., Palus M., Kaspar T., Zemanova M., Majerova K., Hofmannova L., Papezik P., Sikutova S., Rettich F., Hubalek Z., Rudolf I., Votypka J., Modry D. & Ruzek D. (2019) Multiple lineages of Usutu virus (Flaviviridae, Flavivirus) in blackbirds (Turdus merula) and mosquitoes (Culex pipiens, Cx. modestus) in the Czech Republic (2016–2019). Microorganisms  7: 568.  

Králová J., Grybchuk-Ieremenko A., Votýpka J., Novotný V., Kment P., Lukeš J., Yurchenko V. & Kostygov A.Y. (2019) Insect trypanosomatids in Papua New Guinea: high endemism and diversity. International Journal for Parasitology 49: 1075–1086. 

Gruber A., Haferkamp I. (2019) Nucleotide transport and metabolism in diatoms. Biomolecules 9: 761.

Coale T. H., Moosburner M., Horák A., Oborník M., Barbeau K. A., Allen A. E. (2019) Reduction-dependent siderophore assimilation in a model pennate diatom. Proceedings of the National Academy of Sciences of United States of America 116: 23609-23617.

Sharaf A., De Michele R., Sharma A., Fakhari S., Oborník M. (2019) Transcriptomic analysis reveals the roles of detoxification systems in response to mercury in Chromera velia. Biomolecules 9: 647.

Kotsyfakis M., Zarogiannis S. G. and Patelarou E. (2019). The health impact of Saharan dust exposure. International Journal of Occupational Medicine and Environmental Health, 32(6), pp.749-760. https://doi.org/10.13075/ijomeh.1896.01466

Smith S. R., Dupont C. L., McCarthy J. K., Boddrick J. T., Oborník M., Horák A., Füssy Z., Cihlář J., Kleessen S., Zheng H., McCrow J. P., Hixson K. K., Araújo W. L., Nunes-Nesi A., Fernie A., Nikoloski Z., Palsson B. O., Allen A. E. (2019) Evolution and regulation of nitrogen flux through compartmentalized metabolic networks in a marine diatom. Nature Communications 10: 4552.

Treitli S. C., Kolisko M., Husnik F., Keeling P. J., Hampl V. Revealing the metabolic capacity of Streblomastix strix and its bacterial symbionts using single-cell metagenomics. PNAS. 2019, 116(39), 19675-19684. DOI: https://doi.org/10.1073/pnas.1910793116.

Bensaoud, Chaima, Michael Hackenberg a Michail Kotsyfakis. Noncoding RNAs in parasite–vector–host interactions. Trends in parasitology. 2019, 35(9), 715-724. DOI: https://doi.org/10.1016/j.pt.2019.06.012.

Kotsyfakis, Michail a Evridiki Patelarou. MicroRNAs as biomarkers of harmful environmental and occupational exposures: a systematic review. Biomarkers. 2019, 24(7), 623-630. DOI: https://doi.org/10.1080/1354750X.2019.1652348.

Salomaki E. D., Kolisko M. There is treasure everywhere: Reductive plastid evolution in Apicomplexa in light of their close relatives. Biomolecules 2019, 9, 378. https://doi.org/10.3390/biom9080378

Mathur V., Kolisko M., Hehenberger E., Irwin N. A. T., Leander B. S., Kristmundsson A., Freeman M. A., Keeling P. J. Multiple independent origins of apicomplexan-like parasites. Current Biology. 2019, 29(17), 2936-2941. DOI: https://doi.org/10.1016/j.cub.2019.07.019.

Sharaf A., Füssy Z., Tomčala A., Richtová J., Oborník M. (2019) Isolation of plastids and mitochondria from Chromera velia. Planta 250: 1731–1741. 

Eva Hegedűsová, Sneha Kulkarni, Brandon Burgman, Juan D, Alfonzo, Zdeněk Paris, The general mRNA exporters Mex67 and Mtr2 play distinct roles in nuclear export of tRNAs in Trypanosoma brucei, Nucleic Acids Research, Volume 47, Issue 16, 19 September 2019, Pages 8620–8631, https://doi.org/10.1093/nar/gkz671

Jirsová D., Füssy Z., Richtová J., Gruber A., Oborník M. Morphology, ultrastructure, and mitochondrial genome of the marine non-photosynthetic bicosoecid Cafileria marina gen. et sp. nov.. Microorganisms 2019, 7, 240. 

Abdoallah, Sharaf, Ansgar Gruber, Kateřina Jiroutová a Miroslav Oborník. Characterization of Aminoacyl-tRNA synthetases in chromerids. Genes. 2019, 10(8). DOI: https://doi.org/10.3390/genes10080582.

Terán D., Doleželová E., Keough D. T., Hocková D., Zíková A. and Guddat L. W. (2019), Crystal structures of Trypanosoma brucei hypoxanthine – guanine – xanthine phosphoribosyltransferase in complex with IMP, GMP and XMP. FEBS J, 286: 4721-4736. doi:10.1111/febs.14987 

Oborník, Miroslav. Endosymbiotic evolution of algae, secondary heterotrophy and parasitism. Biomolecules. 2019, 9(7), 266. DOI: https://doi.org/10.3390/biom9070266.

Sobotková, Kateřina, William Parker, Jana Levá, Jiřina Růžková, Julius Lukeš a Kateřina Jirků Pomajbíková. Helminth therapy – From the parasite perspective. Trends in parasitology. 2019, 35(7), 501-515. DOI: https://doi.org/10.1016/j.pt.2019.04.009.

Zoltán Füssy, Tereza Faitová, Miroslav Oborník, Subcellular compartments interplay for carbon and nitrogen allocation in Chromera velia and Vitrella brassicaformis, Genome Biology and Evolution, Volume 11, Issue 7, July 2019, Pages 1765–1779, https://doi.org/10.1093/gbe/evz123

Perner, Jan, Robin B. Gasser, Pedro L. Oliveira a Petr Kopáček. Haem biology in metazoan parasites – ‘The bright side of haem’. Trends in parasitology. 2019, 35(3), 213-225. DOI: https://doi.org/10.1016/j.pt.2019.01.001.

Jalovecká, Marie, Daniel Sojka, Mario Ascencio a Leonhard Schnittger. Babesia life cycle – When phylogeny meets biology. Trends in parasitology. 2019, 35(5), 356-368. DOI: https://doi.org/10.1016/j.pt.2019.01.007.

Prokopchuk G., Tashyreva D., Yabuki A., Horak A., Masarova P., Lukes J. Morphological, ultrastructural, motility and evolutionary characterization of two new Hemistasiidae species. Protist. 2019, , 259-282. DOI: https://doi.org/10.1016/j.protis.2019.04.001.

Tereza Pospisilova, Veronika Urbanova, Ondrej Hes, Petr Kopacek, Ondrej Hajdusek, Radek Sima. Tracking of Borrelia afzelii transmission from infected Ixodes ricinus nymphs to mice. Infection and Immunity May 2019, 87 (6) e00896-18; DOI: 10.1128/IAI.00896-18 

Chmelař J., Kotál J., Kovaříková A. and Kotsyfakis M. (2019) The use of tick salivary proteins as novel therapeutics. Front. Physiol. 10:812. doi: 10.3389/fphys.2019.00812

Cihlář, Jaromír, Zoltán Füssy a Miroslav Oborník. Chapter Eight - Evolution of tetrapyrrole pathway in eukaryotic phototrophs. Advances in Botanical Research. 2019, , 273-309. DOI: https://doi.org/10.1016/bs.abr.2018.12.003.

Okamoto N., Gawryluk R. M. R., del Campo J., Strassert J. F. H., Lukes J., Richards T. A., Worden A. Z., Santoro A. E., Keeling P. J.  A revised taxonomy of diplonemids including the Eupelagonemidae n. fam. and a type species, Eupelagonema oceanica n. gen. & sp. Journal of Eukaryotic microbiology. 2019, 66(3), 519-524. DOI: 10.1111/jeu.12679.

Lahr D. J. G., Kosakyan A., Lar E., Mitchell E. A. D., Morais L., Porfirio-Sousa A. L., Ribeiro G. M., Tice A. K., Panek T., Kang S., Brown M. W. Phylogenomics and morphological reconstruction of Arcellinida testate Amoebae highlight diversity of microbial eukaryotes in the neoproterozoic. Current Biology. 2019, 29(6), 991-1001. DOI: https://doi.org/10.1016/j.cub.2019.01.078.

Bianchi, Claretta, Alexei Yu Kostygov, Natalya Kraeva, Kristína Záhonová, Eva Horáková, Roman Sobotka, Julius Lukeš a Vyacheslav Yurchenko. An enigmatic catalase of Blastocrithidia. Molecular and Biochemical parasitology. 2019, 232(111199). DOI: https://doi.org/10.1016/j.molbiopara.2019.111199.

Anna Nenarokova, Kristína Záhonová, Marija Krasilnikova, Ondřej Gahura, Richard McCulloch, Alena Zíková, Vyacheslav Yurchenko, Julius Lukeš. Causes and effects of loss of classical nonhomologous end joining pathway in parasitic eukaryotes. mBio Jul 2019, 10 (4) e01541-19; DOI: 10.1128/mBio.01541-19 

Frolov A. O., Malysheva M. N., Ganyukova A. I., Spodareva V. V., Yurchenko V,. Kostygov A. Y. (2019) Development of Phytomonas lipae sp. n. (Kinetoplastea: Trypanosomatidae) in the true bug Coreus marginatus (Heteroptera: Coreidae) and insights into the evolution of life cycles in the genus Phytomonas. PLoS ONE 14(4): e0214484. https://doi.org/10.1371/journal.pone.0214484

Dolezal P., Makki A., Dyall S. D. (2019) Protein import into hydrogenosomes and mitosomes. In: Tachezy J. (eds) Hydrogenosomes and Mitosomes: Mitochondria of Anaerobic Eukaryotes. Microbiology Monographs, vol 9. Springer, Cham

Rada P., Tachezy J. (2019) The proteome of T. vaginalis hydrogenosomes. In: Tachezy J. (eds) Hydrogenosomes and Mitosomes: Mitochondria of Anaerobic Eukaryotes. Microbiology Monographs, vol 9. Springer, Cham

Hrdý I., Tachezy J., Müller M. (2019) Metabolism of Trichomonad hydrogenosomes. In: Tachezy J. (eds) Hydrogenosomes and Mitosomes: Mitochondria of Anaerobic Eukaryotes. Microbiology Monographs, vol 9. Springer, Cham

Tachezy J., Šmíd O. (2019) Mitosomes in parasitic protists. In: Tachezy J. (eds) Hydrogenosomes and Mitosomes: Mitochondria of Anaerobic Eukaryotes. Microbiology Monographs, vol 9. Springer, Cham

Rada P., Kellerová P., Verner Z. and Tachezy J. 2019. Investigation of the secretory pathway in Trichomonas vaginalis argues against a moonlighting function of hydrogenosomal enzymes. Journal of Eukaryotic Microbiology, https://doi.org/10.1111/jeu.12741

Horák P., Bulantová J., Mikeš L. (2019): Schistosomatoidea and Diplostomoidea. In: Digenetic Trematodes, 2nd Edition (R. Toledo, B. Fried, Eds). Advances in Experimental Medicine and Biology 1154: 217-254. DOI: 10.1007/978-3-030-18616-6 [IF2018=2.126]. Springer ISBN: 978-3-030-18615-9.

Scheiber, Ivo Florin, Jana Pilátová, Ronald Malych, Eva Kotábova, Matyáš Krijt, Daniel Vyoral, Jan Mach, Thibaut Léger, Jean-Michael Camadro, Ondřej Prášil, Emmanuel Lesuisse a Róbert Šuťák. Copper and iron metabolism in Ostreococcus tauri – the role of phytotransferrin, plastocyanin and a chloroplast copper-transporting ATPase. Metallomics. 2019, , 1657-1666. DOI: 10.1039/C9MT00078J.

Vesteg M., Hadariová L., Horváth A., Estraño C. E., Schwartzbach S. D., Krajčovič J. Comparative molecular cell biology of phototrophic euglenids and parasitic trypanosomatids sheds light on the ancestor of Euglenozoa. Biol Rev Camb Philos Soc. 2019 Oct;94(5):1701-1721. doi: 10.1111/brv.12523.

Anna Karnkowska, Sebastian C. Treitli, Ondřej Brzoň, Lukáš Novák, Vojtěch Vacek, Petr Soukal, Lael D. Barlow, Emily K. Herman, Shweta V. Pipaliya, Tomáš Pánek, David Žihala, Romana Petrželková, Anzhelika Butenko, Laura Eme, Courtney W. Stairs, Andrew J. Roger, Marek Eliáš, Joel B. Dacks, Vladimír Hampl. The oxymonad genome displays canonical eukaryotic complexity in the absence of a mitochondrion. Molecular Biology and Evolution. Volume 36, Issue 10. October 2019. Pages 2292–2312. https://doi.org/10.1093/molbev/msz147

Mihalca A. D., Pastrav I. R., Sándor A. D., Deak G., Gherman C. M., Sarmasi A., Votýpka J. (2019) First report of the dog louse fly Hippobosca longipennis in Romania. Medical and Veterinary Entomology. doi: 10.1111/mve.12395

Jaarsma R. I., Sprong H., Takumi K. et al. Anaplasma phagocytophilum evolves in geographical and biotic niches of vertebrates and ticks. Parasites Vectors 12, 328 (2019) doi:10.1186/s13071-019-3583-8

Votýpka J., Brzoňová J., Ježek J., Modrý D. (2019) Horse flies (Diptera: Tabanidae) of three West African countries: A faunistic update, barcoding analysis and trypanosome occurrence. Acta Tropica 197: 105069, 1–8. https://doi.org/10.1016/j.actatropica.2019.105069

Votýpka J., Kment P., Kriegová E.,  Vermeij M. J. A., Keeling P. J., Yurchenko V. , Lukeš J. (2019) High prevalence and endemism of trypanosomatids on a small Caribbean island. Journal of Eukaryotic Microbiology 66: 600–607. https://doi.org/10.1111/jeu.12704

Riseuno J., Spitzova T., Bernal L. J., Munoz C., Lopez M. C., Thomas M. C., Infante J. J., Volf P., Berriatua E. (2019) Longitudinal monitoring of anti-saliva antibodies as markers of repellent efficacy against Phlebotomus perniciosus and Phlebotomus papatasi in dogs . Medical and Veterinary Entomology 33:  99-109. https://doi.org/10.1111/mve.12343

Pereira A., Cristovao J. M., Vilhena H., Martins A., Cachola P., Henriques J., Coimbra M., Catarino A., Lestinova T., Spitzova T., Volf P., Campino L., Maia C. (2019) Antibody response to Phlebotomus perniciosus saliva in cats naturally exposed to phlebotomine sand flies is positively associated with Leishmania infection. Parasites and Vectors 12, Article Number 128. doi:10.1186/s13071-019-3376-0

Jancarova M., Bichaud L., Hlavacova J., Priet S., Ayhan N., Spitzova T., Volf P., Charrel R.N. Experimental infection of sand flies by Massilia virus and viral transmission by co-feeding on sugar meal. Viruses 2019, 11, 332. https://doi.org/10.3390/v11040332

Jack D. Sunter, Ryuji Yanase, Ziyin Wang, Carolina Moura Costa Catta-Preta, Flavia Moreira-Leite, Jitka Myskova, Katerina Pruzinova, Petr Volf, Jeremy C. Mottram, Keith Gull. Leishmania flagellum attachment zone is critical for flagellar pocket shape, development in the sand fly, and pathogenicity in the host. Proceedings of the National Academy of Sciences Mar 2019, 116 (13) 6351-6360; DOI: 10.1073/pnas.1812462116 

Makki A., Rada P, Žárský V., Kereiche S., Kovacik L., Novotny M., Jores T., Rapaport D., Tachezy J. 2019 Triplet-pore structure of a highly divergent TOM complex of hydrogenosomes in Trichomonas vaginalis. PLoS Biology. 17(1):e3000098. doi: 10.1371/journal.pbio.3000098. IF 9,161

Jedličková L., Dvořák J., Hrachovinová I., Ulrychová L., Kašný M., Mikeš L. (2019): A novel Kunitz protein with proposed dual function from Eudiplozoon nipponicum (Monogenean) impairs haemostasis and action of complement in vitro. International Journal for Parasitology, 10.1016/j.ijpara.2018.11.010 

Leontovyč R., Young N. D., Korhonen P. K. et al. Molecular evidence for distinct modes of nutrient acquisition between visceral and neurotropic schistosomes of birds. Sci Rep 9, 1347 (2019) doi:10.1038/s41598-018-37669-2

Ebenezer T. E., Zoltner M., Burrell A. et al. Transcriptome, proteome and draft genome of Euglena gracilis. BMC Biol 17, 11 (2019) doi:10.1186/s12915-019-0626-8

Sima M., Ferencova B., Bhattacharyya T., Miles M. A., Litvinov S. V., Hailu A., et al. (2019) Synthetic peptides as a novel approach for detecting antibodies against sand fly saliva. PLoS Negl Trop Dis 13(1): e0007078. https://doi.org/10.1371/journal.pntd.0007078

Sadlova J., Vojtkova B., Hrncirova K., Lestinova T., Spitzova T., Becvar T., Votypka J., Bates P. & Volf P. (2019) Host competence of African rodents Arvicanthis neumanni, A. niloticus and Mastomys natalensis for Leishmania major. International Journal for Parasitology: Parasites and Wildlife 8: 118–126. 10.1016/j.ijppaw.2019.01.004 

Kostygov A. Y., Butenko A., Yurchenko V. On monoxenous trypanosomatids from lesions of immunocompetent patients with suspected cutaneous leishmaniasis in Iran. Trop. Med. Int. Health, 2019, 24(1): 127-128. https://doi.org/10.1111/tmi.13168

Hampl V., Čepička I., Eliáš M. Was the mitochondrion necessary to start eukaryogenesis? Trends in Microbiology. 2019, 27(2):96-104. https://doi.org/10.1016/j.tim.2018.10.005

Tereza Ševčíková, Tatiana Yurchenko, Karen P. Fawley, Raquel Amaral, Hynek Strnad, Lilia M. A. Santos, Marvin W. Fawley, Marek Eliáš. Plastid genomes and proteins illuminate the evolution of eustigmatophyte algae and their bacterial endosymbionts. Genome Biology and Evolution. Volume 11, Issue 2. February 2019. Pages 362–379. https://doi.org/10.1093/gbe/evz004

Kotál J., Stergiou N., Buša M. et al. The structure and function of Iristatin, a novel immunosuppressive tick salivary cystatin. Cell. Mol. Life Sci. 76, 2003–2013 (2019) doi:10.1007/s00018-019-03034-3

Adl S. M., Bass D., Lane C. E., Lukeš J., Schoch C. L., Smirnov A., Agatha S., Berney C., Brown M. W., Burki F., Cárdenas P., Čepička I., Chistyakova L., del Campo J., Dunthorn M., Edvardsen B., Eglit Y., Guillou L., Hampl V., Heiss A. A., Hoppenrath M., James T. Y., Karnkowska A., Karpov S., Kim E., Kolisko M., Kudryavtsev A., Lahr D. J., Lara E., Le Gall L., Lynn D. H., Mann D. G., Massana R., Mitchell E. A., Morrow C., Park J. S., Pawlowski J. W., Powell M. J., Richter D. J., Rueckert S., Shadwick L., Shimano S., Spiegel F. W., Torruella G., Youssef N., Zlatogursky V. and Zhang Q. (2019), Revisions to the classification, nomenclature, and diversity of eukaryotes. J. Eukaryot. Microbiol., 66: 4-119. https://doi.org/10.1111/jeu.12691

Gahura O., Zíková A. Isolation of F1-ATPase from the parasitic protist Trypanosoma brucei. J Vis Exp. 2019 Jan 22;(143). doi: 10.3791/58334. PubMed PMID: 30735175.

Maslov D. A., Opperdoes F. R., Kostygov A. Y., Hashimi H., Lukeš J., Yurchenko V. Recent advances in trypanosomatid research: genome organization, expression, metabolism, taxonomy and evolution. Parasitology. 2019 Jan;146(1):1-27. doi: 10.1017/S0031182018000951. Epub 2018 Jun 14. PMID: 29898792. 

2018

Mapua M. I. & Votýpka J. In: Modrý D., Pafčo B., Petrželková K. J. & Hasegawa H. (Eds.) (2018) Parasites of apes: An atlas of coproscopic diagnostics. Edition Chiamaira, Frankfurt, Germany, 198 pp. ISBN 978-3899731163.

Petr Rada, Abhijith Radhakrishna Makki, Jan Tachezy. 2018 Targeting of C-tail anchored proteins to Trichomonas vaginalis hydrogenosomes. Mol. Microbiol. doi: 10.1111/mmi.14175. [Epub ahead of print]. IF 3,816

Macháček T., Turjanicová L., Bulantová J., Hrdý J., Horák P., Mikeš L. (2018): Cercarial dermatitis: a systematic follow-up study of human cases with implications for diagnostics. Parasitology Research 117: 3881-3895. DOI: 10.1007/s00436-018-6095-0 [IF2017=2.558]

Roudnický P., Vorel J., Ilgová J., Benovics M., Norek A., Jedličková L., Mikeš L., Potěšil D., Zdráhal Z., Dvořák J., Gelnar M., Kašný M. (2018): Identification and partial characterization of a novel serpin from Eudiplozoon nipponicum (Monogenea, Polyopisthocotylea). Parasite 25: 61. [IF2017=2.069]

Petrů M., Wideman J., Moore K. et al. Evolution of mitochondrial TAT translocases illustrates the loss of bacterial protein transport machines in mitochondria. BMC Biol 16, 141 (2018) doi:10.1186/s12915-018-0607-3

Sumova P., Sima M., Spitzova T., Osman M. E., Guimaraes-Costa A. B., Oliveira F., et al. (2018) Human antibody reaction against recombinant salivary proteins of Phlebotomus orientalis in Eastern Africa. PLoS Negl Trop Dis 12(12): e0006981. https://doi.org/10.1371/journal.pntd.0006981

Velez R., Spitzova T., Domenech E. et al. Seasonal dynamics of canine antibody response to Phlebotomus perniciosus saliva in an endemic area of Leishmania infantum. Parasites Vectors 11, 545 (2018) doi:10.1186/s13071-018-3123-y

Votýpka J., Pafčo B., Modrý D., Mbohli D., Tagg N. & Petrželková K. J. (2018) An unexpected diversity of trypanosomatids in fecal samples of great apes. International Journal for Parasitology: Parasites and Wildlife 7: 322–325.  10.1016/j.ijppaw.2018.09.003 

Frolov A. O., Malysheva M. N., Ganyukova A. I., Yurchenko V., Kostygov A. Y. (2018) Obligate development of Blastocrithidia papi (Trypanosomatidae) in the Malpighian tubules of Pyrrhocoris apterus (Hemiptera) and coordination of host-parasite life cycles. PLoS ONE 13(9): e0204467. https://doi.org/10.1371/journal.pone.0204467

Záhonová K., Füssy Z., Birčák E. et al. Peculiar features of the plastids of the colourless alga Euglena longa and photosynthetic euglenophytes unveiled by transcriptome analyses. Sci Rep 8, 17012 (2018) doi:10.1038/s41598-018-35389-1

Gahura O., Panicucci B., Váchová H., Walker J. E., Zíková A. Inhibition of F(1) -ATPase from Trypanosoma brucei by its regulatory protein inhibitor TbIF(1). FEBS J. 2018 Dec;285(23):4413-4423. doi: 10.1111/febs.14672. Epub 2018 Oct 17. PubMed PMID: 30288927.

Paris, Zdeněk a Juan D. Alfonso. How the intracellular partitioning of tRNA and tRNA modification enzymes affects mitochondrial function. IUBMB life. 2018, 70(12), 1207-1213. DOI: https://doi.org/10.1002/iub.1957.

Sharaf A., Oborník M., Hammad A., El-Afifi S., Marei E. 2018. Characterization and comparative genomic analysis of virulent and temperate Bacillus megaterium bacteriophages. PeerJ 6:e5687 https://doi.org/10.7717/peerj.5687

Oborník, Miroslav. In the beginning was the word: How terminology drives our understanding of endosymbiotic organelles. Microbial Cell. 2018, 6(2), 134-141. DOI: 10.15698/mic2019.02.669.

Oborník, Miroslav. The birth of red complex plastids: One, three, or four times? Trends in parasitology. 2018, , 923-925. DOI: 10.1016/j.pt.2018.09.001.

Kaurov I., Vancová M., Schimanski B., Cadena L.R., Heller J., Bílý T., Potěšil D., Eichenberger C., Bruce H., Oeljeklaus S., Warscheid B., Zdráhal Z., Schneider A., Lukeš J., Hashimi H. (2018) The diverged trypanosome MICOS complex as a hub for mitochondrial cristae shaping and protein import Current Biology 28 : 3393–3407. DOI: 10.1016/j.cub.2018.09.008 

Lukeš, Julius, Richard Wheeler, Dagmar Jirsová a John M. Archibald. Massive mitochondrial DNA content in diplonemid and kinetoplastid protists. IUBMB life. 2018, , 1267-1274. DOI: 10.1002/iub.1894.

Grybchuk, Danyil, Alexei Y. Kostygov, Diego H. Macedo, Jan Votýpka, Julius Lukeš a Vyacheslav Yurchenko. RNA viruses in Blechomonas (Trypanosomatidae) and evolution of Leishmaniavirus. MBIO. 2018, 9(5). DOI: 10.1128/mBio.01932-18. 

Faktorová, Drahomíra, Anita Bär, Hassan Hashimi, et al. TbUTP10, a protein involved in early stages of pre-18S rRNA processing in Trypanosoma brucei. Molecular and Biochemical Parasitology. 2018, (225), 84-93. DOI: https://doi.org/10.1016/j.molbiopara.2018.09.003.

Dixit, Sameer a Julius Lukeš. Combinatorial interplay of RNA binding proteins tune levels of mitochondrial mRNA in trypanosomes. RNA. 2018, 24(11), 1594-1606. DOI: 10.1261/rna.066233.118. 

del Campo J., Kolisko M., Boscaro V., Santoferrara L. F., Nenarokov S., Massana R., et al. (2018) EukRef: Phylogenetic curation of ribosomal RNA to enhance understanding of eukaryotic diversity and distribution. PLoS Biol 16(9): e2005849. https://doi.org/10.1371/journal.pbio.2005849

Eva Pyrihová, Alžběta Motyčková, Luboš Voleman, Natalia Wandyszewska, Radovan Fišer, Gabriela Seydlová, Andrew Roger, Martin Kolísko, Pavel Doležal. A single tim translocase in the mitosomes of Giardia intestinalis illustrates convergence of protein import machines in anaerobic eukaryotes, Genome Biology and Evolution, Volume 10, Issue 10, October 2018, Pages 2813–2822, https://doi.org/10.1093/gbe/evy215

Yurchenko V., & Lukeš J. (2018). Parasites and their (endo)symbiotic microbes. Parasitology, 145(10), 1261-1264. DOI:10.1017/S0031182018001257

Jalovecka M., Hajdusek O., Sojka D., Kopacek P. and Malandrin L. (2018) The complexity of piroplasms life cycles. Front. Cell. Infect. Microbiol. 8:248. DOI: 10.3389/fcimb.2018.00248

Peña-Diaz P., Mach J., Kriegová E., Poliak P., Tachezy J., Lukeš J. (2018) Trypanosomal mitochondrial intermediate peptidase does not behave as a classical mitochondrial processing peptidase. PLoS ONE 13(4): e0196474.  https://doi.org/10.1371/journal.pone.0196474

Peña-Diaz P., & Lukeš J. Fe–S cluster assembly in the supergroup Excavata. J Biol Inorg Chem 23, 521–541 (2018). https://doi.org/10.1007/s00775-018-1556-6

Harmer J., Yurchenko V., Nenarokova A., Lukeš J., & Ginger M. (2018). Farming, slaving and enslavement: Histories of endosymbioses during kinetoplastid evolution. Parasitology, 145(10), 1311-1323. DOI:10.1017/S0031182018000781

Marszewska A., Cichy A., Bulantová J., Horák P., Żbikowska E. 2018. Potamopyrgus antipodarum as a potential defender against swimmer’s itch in European recreational water bodies—experimental study. PeerJ 6:e5045 https://doi.org/10.7717/peerj.5045

Vivas Muñoz J.C., Hilt S., Horák P. et al. Impact of trematode infections on periphyton grazing rates of freshwater snails. Parasitol Res 117, 3547–3555 (2018). https://doi.org/10.1007/s00436-018-6052-y

Willen L., Mertens P., Volf P. (2018) Evaluation of the rSP03B sero-strip, a newly proposed rapid test for canine exposure to Phlebotomus perniciosus, vector of Leishmania infantum. PLoS Negl Trop Dis 12(8): e0006607. https://doi.org/10.1371/journal.pntd.0006607

Sadlova J., Homola M., Myskova J., Jancarova M., Volf P. (2018) Refractoriness of Sergentomyia schwetzi to Leishmania spp. is mediated by the peritrophic matrix. PLoS Negl Trop Dis 12(4): e0006382. https://doi.org/10.1371/journal.pntd.0006382

Halada, P., Hlaváčková, K., Risueño, J., Berriatua, E., Volf, P., Dvořák, V. Effect of trapping method on species identification of phlebotomine sandflies by MALDI-TOF MS protein profiling: Trap effect on sandfly protein profiling. Medical and Veterinary Entomology. 2018, 32. DOI: 10.1111/mve.12305.

Spodareva V. V., Grybchuk-Ieremenko A., Losev A., Votýpka J., Lukeš J., Yurchenko V., Kostygov A. Y. Diversity and evolution of anuran trypanosomes: insights from the study of European species. Parasites & Vectors. 2018, 11(1), 447. DOI: 10.1186/s13071-018-3023-1.

Treitli S. C., Kotyk M., Yubuki N., Jirounková E., Vlásáková J., Smejkalová P., Šípek P., Čepička I., Hampl V. Molecular and morphological diversity of the oxymonad genera Monocercomonoides and Blattamonas gen. nov. Protist. 2018, 169(5), 744-783. DOI: 10.1016/j.protis.2018.06.005.

Vacek V., Novák L. V. F., Treitli S. C., Táborský P., Čepička I., Kolísko M., Keeling P. J., Hampl V. Fe–S Cluster assembly in oxymonads and related protists. Molecular Biology and Evolution. 2018, 35(11), 2712–2718. DOI: 10.1093/molbev/msy168.

Mach J., Bílá J., Ženíšková K., Arbon D., Malych R., Glavanakovová M., Nývltová E., Sutak R. Iron economy in Naegleria gruberi reflects its metabolic flexibility. International Journal for Parasitology. 2018, 48(9-10), 719-727. DOI: 10.1016/j.ijpara.2018.03.005.

Schoener E., Uebleis S. S., Cuk C., Nawratil M., Obwaller A. G., Zechmeister T., et al. (2018) Trypanosomatid parasites in Austrian mosquitoes. PLoS ONE 13(4): e0196052. https://doi.org/10.1371/journal.pone.0196052

Silva F., Kostygov A., Spodareva V., Butenko A., Tossou R., Lukeš J., Yurchenko V., Alves, J. (2018). The reduced genome of Candidatus Kinetoplastibacterium sorsogonicusi, the endosymbiont of Kentomonas sorsogonicus (Trypanosomatidae): Loss of the haem-synthesis pathway. Parasitology, 145(10), 1287-1293. DOI:10.1017/S003118201800046X.

Záhonová K., Petrželková R., Valach M. et al. Extensive molecular tinkering in the evolution of the membrane attachment mode of the Rheb GTPase. Sci Rep 8, 5239 (2018). https://doi.org/10.1038/s41598-018-23575-0

Hackenberg M., Kotsyfakis M. Exosome-mediated pathogen transmission by arthropod vectors. Trends in Parasitology. 2018, 34(7), 549-552. DOI: 10.1016/j.pt.2018.04.001.

Perner J., Kropáčková S., Kopáček P., Ribeiro J. M. C. (2018) Sialome diversity of ticks revealed by RNAseq of single tick salivary glands. PLoS Negl Trop Dis 12(4): e0006410. https://doi.org/10.1371/journal.pntd.0006410

Heiss A. A., Kolísko M., Ekelund F., Brown M. W., Roger A. J., Simpson A. G. B. Combined morphological and phylogenomic re-examination of malawimonads, a critical taxon for inferring the evolutionary history of eukaryotes. Royal society open science. 2018, 5(4). DOI: 10.1098/rsos.171707. ISSN 2054-5703.

Lukeš J., Butenko A., Hashimi H., Maslov D. A., Votýpka J., Yurchenko V. Trypanosomatids are much more than just trypanosomes: Clues from the expanded family tree. Trends in Parasitology. 2018, 34(6), 466-480. DOI: 10.1016/j.pt.2018.03.002.

Procházková M., Panicucci B. & Zíková A. Cultured bloodstream Trypanosoma brucei adapt to life without mitochondrial translation release factor 1. Sci Rep 8, 5135 (2018). https://doi.org/10.1038/s41598-018-23472-6

Perner J., Kotál J., Hatalová T., Urbanová V., Bartošová-Sojková P., Brophy P. M., Kopáček P. Inducible glutathione S-transferase (IrGST1) from the tick Ixodes ricinus is a haem-binding protein. Insect Biochemistry and Molecular Biology. 2018, 95, 44-54. DOI: 10.1016/j.ibmb.2018.02.002.

Tashyreva D., Prokopchuk G., Votýpka J., Yabuki A., Horák A., Lukeš J. Life cycle, ultrastructure, and phylogeny of new diplonemids and their endosymbiotic bacteria. MBio. 2018, 9(2). DOI: 10.1128/mBio.02447-17.

Lynn D. H., Kolísko M., Bourland W. Phylogenomic analysis of Nassula variabilis n. sp., Furgasonia blochmanni, and Pseudomicrothorax dubius confirms a Nassophorean clade. Protist. 2018, 169(2), 180-189. DOI: 10.1016/j.protis.2018.02.002.